About DUPIXENT

The First-of-Its-Kind Asthma Treatment

DUPIXENT blocks two key sources of inflammation in the lungs to help
those living with moderate-to-severe asthma breathe easier and fight
their asthma every day.

Benefits With Every Breath

Improve lung function so you can breathe better in as little as 2 weeks

Help prevent severe asthma attacks

Can reduce or even completely
eliminate oral steroids

Have an Effective conversation with your Doctor

Our goal is for you to get the most out of the visit to the doctor. Download the Doctor Discussion Guide for tips on how to drive a productive conversation, and listen to the audio file for an example conversation.

Doctor Discussion Guide 797 KB
Patients can take part in treatment decisions. Listen to a patient self-advocate for themselves and DUPIXENT with their doctor.

In about 40 seconds you’re going to hear how a patient and doctor might discuss life with moderate-to-severe asthma that is not well controlled and potential treatment with DUPIXENT® (dupilumab). DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age. Let’s take a listen.

DOCTOR: While your asthma is still uncontrolled, it looks like your symptoms haven’t gotten worse, and your test results are about the same as last time. That’s good. I don’t think we’ll have to change your medications at this point.

PATIENT: OK…but I was hoping to talk to you about how my asthma’s really been affecting me.

DOCTOR: OK, tell me more.

PATIENT: Well, there’s so much I can’t do. Like the other day: I was at a birthday party for a friend [pause] and got winded singing “Happy Birthday.” So, of course, now I’m worried about having issues swimming and keeping up with my family next month when we go on our beach trip.

DOCTOR: Are you taking your asthma medications every day like we discussed?

PATIENT: Yeah, I take them, [pause] but it’s not enough. My chest still gets tight, and I feel like I can’t breathe; I can’t seem to stop having asthma attacks. Is there something else I can try?

DOCTOR: Well, you know, sometimes asthma can be hard to control. But I didn’t know it was having such a big impact on your daily life, so I’m glad you brought it up. There are other medicines we can consider.

PATIENT: Actually, that’s one of the things I wanted to talk to you about. I saw something about this medicine called DUPIXENT. Can you tell me anything about it?

DOCTOR: I do have patients who take DUPIXENT. Some have said it has helped prevent asthma attacks from even happening.

PATIENT: That sounds like what I need.

DOCTOR: Before we make a decision, I’d like to tell you a little more about DUPIXENT. Would that be OK?

PATIENT: Sure.

DOCTOR: DUPIXENT is a subcutaneous injection. So…[patient interrupts]

PATIENT: What does sub…subcutaneous mean?

DOCTOR: It just means under the skin. After the initial injection, you would be giving yourself an injection under the skin every other week. We’ll make sure you’re comfortable with the process before you start at home.

PATIENT: Are there any side effects?

DOCTOR: The most common side effects include injection site reactions, pain in the throat—also called oropharyngeal pain—and cold sores in the mouth or on the lips.

PATIENT: OK.

DOCTOR: So, do you think you’re interested in trying DUPIXENT?

PATIENT: Yes! I’m ready to try something different.

DOCTOR: OK, let’s talk about how to get started. [pause] It’s an add-on medication, so you’ll still need to take your regular asthma medicines.

PATIENT: How will I know DUPIXENT is working?

DOCTOR: Give it at least two weeks. After that you may notice that you can breathe better. You may even be able to reduce or eliminate your use of oral steroids. We’ll schedule a follow-up so I can check your progress.

PATIENT: Thanks. I’m looking forward to doing more.

 

DUPIXENT significantly improved lung function and helped prevent asthma attacks.

Up to 81% Fewer
Asthma Attacks*†

The benefits and risks of
DUPIXENT were evaluated in 3
clinical studies with 2888 patients.

86% of People Reduced
or Eliminated Their Oral
Steroid Dose

In a study of people
dependent on oral corticosteroids

  • *In those with high eosinophil counts (a type of white blood cell).
  • The annual rate of severe asthma attacks was a 0.20 with DUPIXENT 300 mg vs 1.04 with placebo.
  • In a clinical study with DUPIXENT 300 mg + Standard of Care vs 68% with placebo + Standard of Care.

The most common side effects include injection site reactions, pain in the
throat (oropharyngeal pain) and cold sores in your mouth or on your lips.