About Persistent Asthma

A hope for
asthma

Have you thought about a life with less asthma? It’s important to
understand the current level of your asthma control.

Evolving
Asthma Science

Scientific advances have found that Type 2 inflammation is one of the major sources of persistent, moderate-to-severe asthma.

With moderate-to-severe asthma, there’s a constant underlying inflammation in the lungs, regardless of whether you have any symptoms.

Even with the use of oral steroids—like prednisone—and other asthma treatments, moderate-to-severe asthma can be very hard to control.

How an Asthma Attack Feels

Hear from DUPIXENT patients as they describe what it feels like when they experience an asthma attack. Does their description sound similar to your experience?

Transcript

VO:

DUPIXENT (dupilumab) is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for Full Prescribing information.

Before starting DUPIXENT, you should talk to your doctor about all the medical conditions you have or medications you are taking.

You and your doctor should also discuss the potential benefits and risks of treatment with DUPIXENT including the most common side effects such as injection site reactions, and some serious side effects such as allergic reactions including anaphylaxis and inflammation of your blood vessels.

RACHEL:

When I start having an asthma attack, I feel immediately exhausted.

MARLENA:

It’s similar to trying to blow out of a straw, if you could imagine the very little amount of air that you can actually blow through a straw.

RACHEL:

My chest starts feeling tight and feels very heavy. I get a little cough and wheeze.

PAMELA:

I equate it to how someone may feel if they’re drowning. You’re just trying to grasp for breath. It's like someone is taking your lungs and just squeezing them, and it's extremely scary.

RACHEL:

Then, you notice the wheeze isn’t going away. The tightness isn’t going away, and you- you kind of freeze.

MARLENA:

And you’re hot, and you’re sweaty, and you just can’t get any air, and it feels like a fish out of water.

PAMELA:

You try not to panic, and you tell yourself to be calm, but you're still panicking because you can't breathe.

MARLENA:

That’s how I would describe an asthma attack.

VO:

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines; have asthma and use an asthma medicine; and have atopic dermatitis or CRSwNP, and also have asthma. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.

The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.

Please see adjacent links for full Prescribing Information including Patient Information.

These are Signs of Uncontrolled Asthma.

If you don't think your asthma is controlled, take the opportunity to get more information about DUPIXENT and download our discussion guide to talk to your doctor about whether DUPIXENT is an option for you.

Learn more about Dupixent

Back

Identify the Signs of Control

Here are a few key factors that may indicate that
your persistent, moderate-to-severe asthma isn’t
well controlled:

In the past month, you’ve woken up at night because of your asthma
You’ve gone to the emergency room because of your asthma at least once in the past year
You limited or missed an activity because of an attack
You use your rescue inhaler more than twice a week

Does any of this sound familiar?

Yes, it Does

I went from leading a pretty active lifestyle to scheduling my life around doctor’s appointments, missing activities with family and friends, and living in fear of my next attack.

- Pam, DUPIXENT MyWay®
Patient Ambassador

Individual results may vary.

Watch Pam’s story

BETTER BREATHING.
LESS ORAL STEROIDS.

While oral steroids are helpful when prescribed, there is some medical concern over long-term use: mood changes, weight gain, diabetes, and vision problems.

Managing persistent, moderate-to-severe asthma is not easy. But, adding DUPIXENT may help.