Frequently Asked Questions

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral corticosteroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines.

DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing.

DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.

DUPIXENT blocks two key sources of inflammation in your lungs to help prevent asthma attacks and reduce asthma symptoms.

Do not use DUPIXENT if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your doctor about all your medical conditions, including if you:

• Have a parasitic (helminth) infection.
• Are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
• Are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
• Are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines; have asthma and use an asthma medicine; and have atopic dermatitis or CRSwNP, and also have asthma. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

DUPIXENT can cause serious side effects, including:

• Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and go to the nearest hospital emergency room if you get any of the following symptoms:

  • Breathing problems
  • Fever
  • General ill feeling
  • Swollen lymph nodes

  • Swelling of the face, mouth, and tongue
  • Hives
  • Itching

  • Fainting, dizziness, feeling lightheaded (low blood pressure)
  • Joint pain
  • Skin rash

• Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your doctor right away if you have:

  • Rash
  • Shortness of breath
  • Persistent fever
  • Chest pain

  • A feeling of pins and needles or numbness of your arms or legs

The most common side effects of DUPIXENT include:

• Injection site reactions
• Pain in the throat (oropharyngeal pain)
• High count of a certain white blood cell (eosinophilia)

Tell your doctor if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

DUPIXENT is given as an injection under the skin (subcutaneous injection). DUPIXENT can be injected into the thigh, stomach (except for the 2 inches around the belly button), or outer area of the upper arm (if caregiver injects). A different site should be chosen each time DUPIXENT is injected.

• Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it.
• Follow your doctor's instructions and read the Instructions for Use for full details on preparation, administration, and disposal of your injection.

There are a few things to consider when talking to your doctor to see if DUPIXENT is right for you. Be sure to share symptoms you’ve recently experienced, and think of questions you want to ask. Download the Doctor Discussion Guide to help drive a productive appointment with your doctor.

For more information about DUPIXENT support, you can enroll in DUPIXENT MyWay®, a program that can provide:

• Tips and tools to help with your uncontrolled moderate-to-severe asthma.
• Additional injection training. Your doctor will show you the proper procedure first and decide whether you can self-inject.
• Financial support for eligible commercially insured patients.
• Assistance with insurance questions.
• Assistance locating a pharmacy that can dispense your DUPIXENT prescription.

Sign up or call a support coordinator at 1‑844‑DUPIXENT (1‑844‑387‑4936) to learn more.

DUPIXENT is a specialty drug, often ordered differently than a traditional drug, and may have specific requirements after your doctor prescribes it.

Your insurance provider may require that you order DUPIXENT through a specialty pharmacy in-network with your plan. These pharmacies can:

• Coordinate directly with your doctor.
• Manage the handling and service requirements of specialty drugs.
• Ship your medication directly to your home in a special cooler to help make sure the correct temperature is maintained through the process.
• Stay in contact with you and your doctor throughout the treatment.

What's Next After
You're Prescribed?

Notify your pharmacy. In fact, when you take medications that require refills regularly over time, it’s always good to periodically check that your pharmacy has your most up-to-date insurance information on file. This can help you avoid potential delays in getting your prescription.

Contact 1‑844‑DUPIXENT (1‑844‑387‑4936) to speak to a DUPIXENT MyWay® Nurse Educator if you have additional questions.

Through the Patient Assistance Program, eligible patients who are uninsured or whose insurance does not cover DUPIXENT could receive DUPIXENT free of charge.

Those who may qualify must be at least 18 years of age or older, a resident of the 50 United States, the District of Columbia, or Puerto Rico, and demonstrate a financial need with a total annual adjusted gross income of $100,000 or less.