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DUPIXENT se estudió en 3 ensayos clínicos con más de 2,800 pacientes de 12 años o más con asma moderada a grave.
BENEFICIOS CON CADA RESPIRACIÓN
Obtén más información sobre los estudios clínicos de DUPIXENT en pacientes con asma.
Mejoramiento de
la función pulmonar
en apenas 2 semanas
HASTA UN 81% MENOS
ATAQUES DE ASMA*†
UN 86% DE LAS PERSONAS REDUJERON O ELIMINARON SUS DOSIS DE ESTEROIDES ORALES‡
En un estudio de personas dependientes de corticosteroides orales.
DUPIXENT tenía un perfil de seguridad demostrado en los ensayos clínicos. Los efectos secundarios más comunes incluyen reacciones en el lugar de la inyección, dolor de garganta (dolor orofaríngeo) y recuento alto de ciertos glóbulos blancos (eosinofilia).
Ver los posibles efectos secundarios de DUPIXENT en pacientes con asma eosinofílica o asma dependiente de corticosteroides orales moderada a grave.
- *En aquellas personas con recuentos altos de eosinófilos (un tipo de glóbulo blanco).
- †La tasa anual de ataques severos de asma fue de 0.20 con DUPIXENT 300 mg frente a 1.04 con placebo.
- ‡En un estudio clínico con DUPIXENT 300 mg + tratamiento estándar frente a un 68% con placebo + tratamiento estándar. No dejes de tomar tus medicamentos corticosteroides a menos que te lo indique tu proveedor de atención médica. Esto puede hacer que reaparezcan otros síntomas que fueron controlados por el medicamento corticosteroide.
Esto es lo que debes saber sobre los
pacientes que participaron en
estos estudios:
RESULTADOS EN NIÑOS
También se demostró que DUPIXENT mejora la función pulmonar y previene los
ataques de asma en niños de 6 a 11 años.
CONSIDERING DUPIXENT
SHARRON: I have lived with severe asthma most of my life. It developed early on when I was in middle school, and then as an adult, I had to use my rescue inhaler very frequently and the nebulizer as well.
RACHEL: I was diagnosed with severe asthma at the age of ten.
I had a lot of coughing, wheezing, feeling short of breath. My chest would get tight. We tried a lot of different asthma medications, but I would still end up in the hospital a couple of times a year. It had a really big impact on my life.
SHARRON: So, I love to sing, and singing was challenging to carry a note all the way through. I just couldn’t breathe. It was just hard to breathe.
RACHEL: The hardest thing to deal with was my wheezing. It was all the time. If we were sitting in a quiet classroom, the people next to me could hear me wheezing.
SHARRON: My asthma was not under control. Every day I woke up knowing that there’s a chance that I could have a severe asthma attack and go to the ER. It was definitely a weight on my mind with living like that, and I felt hopeless.
RACHEL: I had a really bad asthma attack when I was twenty-five years old that resulted in me being in the hospital for a week and after that, I was like, “Enough is enough!” I have to do something more to control my asthma.
SHARRON: So, my doctor treated my asthma with rescue inhalers, anti-inflammatories, oral steroids and long-acting inhalers. They weren’t managing the asthma well; it was not controlled.
One day on a follow-up appointment, my doctor brought up DUPIXENT as an add-on therapy. He talked about it being a biologic, what that was, and I was ready for it.
If there was a chance that it could help control my asthma, then I was ready for it and willing to do whatever I needed to do.
RACHEL: When my doctor suggested DUPIXENT, I was open to it. We had a candid conversation. I asked a lot of questions. She explained to me what was going on in my body and that DUPIXENT could work for patients like me, so I wanted to try it.
SHARRON: Before I started DUPIXENT, I told my doctor about all the medical conditions I had, and medications I was taking.
RACHEL: My doctor and I went over the potential benefits and risks of treatment, including the most common side effects such as injection site reactions.
SHARRON: We also talked about some serious side effects such as allergic ractions, including anaphylaxis, and inflammation of your blood vessels.
RACHEL: After starting DUPIXENT, I was able to do some of my simple, everyday activities without my asthma getting in the way as often, like running around the yard with my dogs, helping with the outdoor chores.
SHARRON: Over time I noticed that the wheezing decreased, I didn’t have to use my rescue inhaler as often, and I think the best of all was that I was able to sing and hold the note.
RACHEL: I never thought that I would be where I am in my asthma journey. It’s a very good feeling. I feel a lot of relief knowing that my asthma is better controlled.
SHARRON: It feels great to be able to manage my asthma better.
RACHEL: I’ve learned to be a good advocate for myself and that I do not have to accept uncontrolled asthma.
VO:
Important Safety Information
Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.
Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
- have a parasitic (helminth) infection
- are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
- are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
- There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
- are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.
DUPIXENT can cause serious side effects, including:
- Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
- Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.
The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.
Please see accompanying full Prescribing Information including Patient Information.
Indication
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.
TAKING DUPIXENT
RACHEL: It's really important to me to take DUPIXENT as directed by my doctor. I make it a priority. My severe asthma is something I need to keep controlled. It's not going away. It's something I live with, and I need to manage it.
SHARRON: I understand that my severe asthma is a chronic condition, there will always be underlying inflammation, and that my severe asthma will never quit and neither can I.
RACHEL: I feel motivated to stay on my treatment schedule, because I know what it feels like not to be able to breathe well, and I want to do everything I can to help avoid being in that situation.
SHARRON: What motivates me to stay on treatment is knowing that my current treatment plan is working. With DUPIXENT I’m able to do more of what I want to do and with less asthma.
RACHEL: Having a routine has definitely helped me stay on track. I take my DUPIXENT every two weeks. It’s a system I’m comfortable with.
SHARRON: So, I have a DUPIXENT reminder on my calendar and an alarm set on my phone. It’s scheduled for every two weeks, and it’s like a ritual for me. It is how I take care of myself.
RACHEL: When I first started out on DUPIXENT, the DUPIXENT MyWay® patient support program was really helpful. They are there to help you answer questions about DUPIXENT. They can help you set up reminders to start and maintain a routine. But remember your doctor is always the best source of information.
SHARRON: My doctor recommended that I reach out to DUPIXENT MyWay after he wrote the prescription. I’m so glad he did! They’ve been a tremendous resource for me, and it’s good to know that I can reach out to them.
RACHEL: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and the medications I was taking.
SHARRON: My doctor and I went over the potential benefits and risks of treatment, including the most common side effects such as injection site reactions.
RACHEL: We also talked about some of the serious side effects such as allergic reactions, including anaphylaxis, and inflammation of your blood vessels.
SHARRON: Over time, I’ve definitely gotten more used to taking DUPIXENT. It’s a part of my life just like going to the doctor.
RACHEL: I am comfortable taking DUPIXENT every two weeks. I know that it helps control my asthma, and I feel that it's helping prevent me from another asthma attack. It’s what my doctor and I decided I need to do.
VO:
Important Safety Information
Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.
Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
- have a parasitic (helminth) infection
- are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
- are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
- There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
- are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.
DUPIXENT can cause serious side effects, including:
- Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
- Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.
The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.
Please see accompanying full Prescribing Information including Patient Information.
Indication
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.
STAYING ON TRACK
Did you know that each time your DUPIXENT® (dupilumab) is shipped to you, you’re getting more than just your medicine in that delivery box?
It’s true!
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT is not used to treat sudden breathing problems.
With each delivery of DUPIXENT, you’re also getting an opportunity for better control of your asthma.
Just imagine what that improvement could mean for you.
Each time you open that box, think about how DUPIXENT may help you do more of what you want in life.
What could you do with more freedom from asthma?
What could you spend more of your time doing?
And remember, if you take your DUPIXENT every other week as prescribed, you’re not only working to help prevent attacks, you’re also giving yourself the opportunity to do more with less asthma.
And don’t forget, DUPIXENT MyWay® Nurse Educators are just a phone call away.
Indication
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.
Important Safety Information
Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.
Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
- have a parasitic (helminth) infection
- are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
- are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
- There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
- are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.
DUPIXENT can cause serious side effects, including:
- Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
- Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.
The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.
Please see accompanying full Prescribing Information including Patient Information.
Indication
DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.
TEN UNA CONVERSACIÓN
PRODUCTIVA CON TU MÉDICO
Nuestro objetivo es que tú o tu ser querido aprovechen al máximo la visita al médico. Completa nuestra guía de discusión personalizada para ayudarte a tener una conversación productiva durante tu próxima visita.
Obtén la Guía de discusión para
hablar con el médico
Ahora que estoy en tratamiento con
DUPIXENT, puedo DISFRUTAR MÁS de las
cosas que me gusta hacer. Sigo haciendo
todo lo posible para evitar provocar mi
asma, pero puedo ser más activo.
- Tim, Paciente embajador de
DUPIXENT MyWay®
Los resultados individuales pueden variar.
para obtener más información sobre las opciones
de dosificación y administración.