Frequently Asked Questions

Learn About DUPIXENT

To help you understand uncontrolled moderate-to-severe eczema (atopic dermatitis) and how DUPIXENT may help treat it, we’ve provided answers to the most common questions. As always, be sure to ask your doctor any additional questions you may have.



DUPIXENT is the first biologic medication approved by the FDA for people 12 years and older with moderate-to-severe eczema (atopic dermatitis) who are not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT is not a steroid and can be taken with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 12 years of age.

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Do not use DUPIXENT if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • Have eye problems (if you also have atopic dermatitis).
  • Have a parasitic (helminth) infection.
  • Are taking oral, topical, or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
  • Are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
  • Are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • Pregnancy Registry. There is a pregnancy registry for women who take DUPIXENT during pregnancy. The purpose of this registry is to collect information about your health and your baby’s health. You can talk to your healthcare provider or contact 1-877-311-8972 or go to to enroll in this registry or get more information.
  • Are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. If you are taking asthma medicines, do not change or stop your asthma medicine without talking to your healthcare provider.

  • The effectiveness of DUPIXENT has been studied in three well-controlled medical studies with approximately 2,100 adults with uncontrolled moderate-to-severe eczema.
  • Patients enrolled in these studies were not well controlled with prescription therapies used on the skin (topical), or who could not use topical therapies.
  • DUPIXENT was shown to be effective in these studies when taken alone and when taken with topical corticosteroids.
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DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms:
    • breathing problems
    • fever
    • general ill feeling
    • swollen lymph nodes
    • swelling of the face, mouth, and tongue
    • hives
    • itching
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • joint pain
    • skin rash
  • Eye problems. If you have atopic dermatitis, tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.

The most common side effects of DUPIXENT include:

  • Injection site reactions
  • Eye and eyelid inflammation, including redness, swelling and itching have been seen in patients with atopic dermatitis
  • Pain in the throat (oropharyngeal pain)
  • Cold sores in your mouth or on your lips

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


  • DUPIXENT is given as an injection under the skin (subcutaneous injection) at different injection sites. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider.
  • The recommended dose of DUPIXENT for adult patients is an initial dose of 600 mg (two 300 mg injections), followed by 300 mg given every other week.
  • Talk to your healthcare professional and see the detailed Instructions for Use that comes with DUPIXENT for information on how to prepare and inject DUPIXENT and how to properly store and throw away (dispose of) used DUPIXENT Pre-filled Syringes prior to taking the drug.

Watch this video to learn how to administer DUPIXENT.

DUPIXENT can be injected into the thigh, stomach (except for the 2 inches around the belly button) or outer area of the upper arm (if caregiver injects). A different site should be chosen each time DUPIXENT is injected.

  • Follow your healthcare provider's instructions and read the Instructions for Use for full details on preparation, administration and disposal of your injection.

Download Instructions for Use PDF 234 KB


For more information about DUPIXENT support and services, you can enroll in DUPIXENT MyWay®, a program that can provide:

  • Tips and tools to help with your uncontrolled moderate-to-severe eczema (atopic dermatitis).
  • Additional injection training. Your doctor will show you the proper procedure first and decide whether you can self-inject.
  • Financial support for eligible commercially insured patients.
  • Assistance with insurance questions.
  • Assistance locating a pharmacy that can dispense your DUPIXENT prescription.

Sign up or call a support coordinator at 1-844-DUPIXENT (1-844-387-4936) to learn more.

See Support Options

Certain retail pharmacies or specialty pharmacies can fill your prescription. These pharmacies can:

  • Coordinate directly with your doctor.
  • Manage the handling and service requirements of specialty drugs.
  • Ship your medication directly to your home in a special cooler, to help make sure the correct temperature is maintained through the process.
  • Stay in contact with you and your doctor throughout the treatment.

Notify your pharmacy. In fact, when you take medications that require refills regularly over time, it’s always good to periodically check that your pharmacy has your most up-to-date insurance information on file. This can help you avoid potential delays in getting your prescription.

Contact 1-844-DUPIXENT (1-844-387-4936) to speak to a DUPIXENT MyWay® Nurse Educator if you have additional questions.