DUPIXENT is a prescription treatment used with other medicines to treat chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with CRSwNP under 18 years of age.
Do not use DUPIXENT if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.
Before using DUPIXENT, tell your doctor about all your medical conditions, including if you:
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines; have asthma and use an asthma medicine; and have CRSwNP, and also have asthma. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
The effectiveness and safety of DUPIXENT has been studied in 2 clinical trials with 724 adults with uncontrolled chronic rhinosinusitis with nasal polyposis (CRSwNP).
Patients enrolled in these studies included subjects with CRSwNP despite prior sino-nasal surgery or treatment with, or who were ineligible to receive or were intolerant to, systemic corticosteroids in the past 2 years. Patients with chronic rhinosinusitis without nasal polyposis were not included in these trials.
DUPIXENT can cause serious side effects, including:
Some of the most common side effects in patients with chronic rhinosinusitis with nasal polyposis include:
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
DUPIXENT is given as an injection under the skin (subcutaneous injection) at different injection sites. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it.
Watch this video to learn how to administer DUPIXENT.
Pre-filled Syringe Instructions For Use
DUPIXENT can be injected into the thigh, stomach (except for the 2 inches around the belly button), or outer area of the upper arm (if caregiver injects). A different site should be chosen each time DUPIXENT is injected.
Pre-filled Syringe Instructions For Use
For more information about DUPIXENT support and services, you can enroll in DUPIXENT MyWay®, a program that can provide:
Sign up or call a support coordinator at 1-844-DUPIXENT (1-844-387-4936) to learn more.
Certain retail pharmacies or specialty pharmacies can fill your prescription. These pharmacies can:
Notify your pharmacy. In fact, when you take medications that require refills regularly over time, it's always good to periodically check that your pharmacy has your most up-to-date insurance information on file. This can help you avoid potential delays in getting your prescription.
If you have additional questions, contact 1-844-DUPIXENT (1-844-387-4936) to enroll in DUPIXENT MyWay® and speak to a Nurse Educator.
With the DUPIXENT MyWay Copay Card, eligible patients may pay as little as $0 for every fill of DUPIXENT if they meet the following requirements*:
Through the Patient Assistance Program, eligible patients who are uninsured or whose insurance does not cover DUPIXENT could receive DUPIXENT free of charge.
Those who may qualify must be at least 18 years of age or older, a resident of the 50 United States, the District of Columbia, or Puerto Rico, and demonstrate a financial need with a total annual adjusted gross income of $100,000 or less.
The DUPIXENT MyWay team will research each patient’s situation and determine eligibility. For more information, call 1-844-DUPIXENT (1-844-387-4936), option 1.