Glossary

Glossary

Take a minute to learn about common medical terms and key words associated with uncontrolled moderate-to-severe eczema (atopic dermatitis) and DUPIXENT.


A
Allergen

A typically harmless substance that causes a response of the immune system. Examples of allergens include pollen, dust mites, animal dander and mold.

Allergy

A chronic condition characterized by an unusual reaction of the immune system to a typically harmless substance, called an allergen. See Allergen.

Atopic dermatitis (also called atopic eczema)

A chronic skin disease and the most common type of eczema. It is characterized by skin inflammation and itch. Scratching the skin results in redness, swelling, cracking, oozing, crusting and scaling. Atopic dermatitis is not contagious. See Eczema, Dermatitis and Inflammation.


B
Biologic

Biologics are a different class of medication. They are different from commonly used medications such as corticosteroids. Some biologics may target only specific reactions within the body and are available as injections.


C
Chronic

Lasting for a long time or occurring over and over for a long time.

Corticosteroids

Medications that decrease inflammation. Steroid creams and ointments are frequently used to treat atopic dermatitis.


D
DUPIXENT MyWay®

A program to provide support for patients starting DUPIXENT. Get ongoing, personalized nursing support 24/7; help scheduling monthly prescription refills and deliveries; and in-home, in-office or online supplemental injection training.


E
Eczema

A group of skin conditions characterized by skin inflammation, rash and itch. There are many different types of eczema, and atopic dermatitis is the most common of them.


F
Flare-up

An instance when disease symptoms get worse.


I
Immune system

The defense system that protects your body against harmful substances and invaders, such as bacteria and viruses. The immune system is made up of many different cell types and organs.

Inflammation

Your body’s response to damage caused by bacteria, harmful substances, high temperature or other factors. The damaged cells produce chemical signals that attract white blood cells that cause swelling in the surrounding tissues. Inflammation can lead to itchiness and redness.

Itch

An unpleasant sensation in the skin that makes you want to scratch.


O
Oozing

The weeping of fluid on the skin surface as a result of scratching. When the fluid dries out, crusting is created.


P
Placebo

An inactive substance used in clinical studies to make it easier to determine the true effects of the active drug that is being tested.


R
Rash

A change in the way skin looks or feels. Skin may change color, may become bumpy, dry, itchy or cracked.


S
Scaling

Flakes or plates of dry, hard outer layer of skin.

Scratch

To scrape your skin with nails, often to relieve itching.

Sharps disposal container

A container used to dispose of used syringes and needles.


T
Topical

A medicine applied to the skin.

Triggers

Things that can make your atopic dermatitis worse. Examples of triggers include dry skin, irritants, stress, hot and cold temperature, sweating, infection, allergens and hormones.