DUPIXENT should be refrigerated at 36 °F to 46 °F in the original carton to protect from light.

If necessary, DUPIXENT may be kept at room temperature up to 77 °F (25 °C) for a maximum of 14 days. Do not store above 77 °F (25 °C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded.

Do not heat or put DUPIXENT into direct sunlight.

Do not freeze. Do not shake.