DUPIXENT is a prescription medicine used to treat adults and children 2 years of age and older with chronic spontaneous urticaria (CSU) who continue to have hives that are not controlled with H1 antihistamine treatment. DUPIXENT is not used to treat any other forms of hives (urticaria).
THELMA,
Actual DUPIXENT patient
since late 2025.
Individual results may vary.
DUPIXENT was studied in two 24-week clinical trials in 284 patients ages 12 years and older with chronic
spontaneous urticaria (CSU) who continued to have hives despite taking H1 antihistamines. All patients
remained on antihistamines during the trials.
DUPIXENT's use for treating CSU in children ages 2-11 years is supported by the results from two studies that included patients
12 years of age and older with CSU.
*Patients rated their itch daily (on a scale from 0 to 3) for 7 days (maximum score of 21), and this number was compared to their baseline score.
†Patients rated their hives daily (on a scale from 0 to 3) for 7 days (maximum score of 21). This score was added to their itch severity score and compared to
the baseline score.
View the possible side effects of DUPIXENT.
The safety of DUPIXENT was assessed in 18 patients 2-11 years of age who received DUPIXENT based on weight. No new side
effects were identified in pediatric patients 2-11 years old who received DUPIXENT.