DUPIXENT helps manage chronic rhinosinusitis with nasal polyps (CRSwNP) and is proven to help improve breathing by relieving nasal congestion and reducing nasal polyps.

Targets Two Of The Sources
Of Type 2 Inflammation

DUPIXENT is a form of medicine called a biologic that works differently by targeting two of the sources of Type 2 inflammation, an underlying cause of Nasal Polyps.

How It Helps

DUPIXENT improves CRSwNP by
blocking two of the key sources of
Type 2 inflammation. This can result in
shrinking of nasal polyps and reducing
the need for surgery.

Proven Results

83% fewer patients required nasal polyp surgery while taking DUPIXENT.*

*Compared to placebo


Ask your doctor if DUPIXENT
is right for you

If you have any of the following characteristics,
fill out our doctor discussion guide and speak to
your doctor about DUPIXENT.

Have uncontrolled symptoms
despite the use of oral steroids

Have had previous surgeries
to remove polyps


Accessing and affording DUPIXENT

Explore costs and eligibility for the
DUPIXENT MyWay® Copay Card

The DUPIXENT MyWay Copay Card may help
eligible CRSwNP patients cover the out-of-pocket
cost of DUPIXENT.

Check copay
card eligibility


DUPIXENT is a prescription treatment used with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with CRSwNP under 18 years of age. DUPIXENT is not a steroid or immunosuppressant.

Fill out your personalized doctor discussion guide and ask your doctor if DUPIXENT may be right for you.  

Type 2 inflammation is an underlying cause of CRSwNP in 80% of patients. CRSwNP is predominantly characterized by Type 2 inflammation of the nose and paranasal sinuses. DUPIXENT blocks 2 key sources of type 2 inflammation and shrinks nasal polyps and reduces the need for surgery.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms:
    • breathing problems or wheezing
    • fast pulse
    • fever
    • general ill feeling
    • swollen lymph nodes
    • swelling of the face, lips, mouth, tongue, or throat
    • hives
    • itching
    • nausea or vomiting
    • fainting, dizziness, feeling lightheaded
    • joint pain
    • skin rash
    • cramps in your stomach-area
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have:
    • rash
    • worsening shortness of breath
    • persistent fever
    • chest pain
    • a feeling of pins and needles or numbness of your arms or legs
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with chronic rhinosinusitis with nasal polyposis include:

  • injection site reactions
  • eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision
  • high count of a certain white blood cell (eosinophilia)
  • trouble sleeping (insomnia)
  • toothache
  • gastritis
  • joint pain (arthralgia)

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.