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CRSwNP can be a difficult condition to navigate. If you or your loved one are suffering from uncontrolled CRSwNP, partnering with a specialist might be the appropriate next step.

Ask a specialist

Get common questions about nasal polyps answered and learn about DUPIXENT as a treatment option from a board-certified nasal polyps specialist.

You can use this to help start that conversation with your doctor to see if DUPIXENT may be right for you.

Dr. Damask:

Hi, I’m Dr. Damask and I’m a board-certified otolaryngologist. I’m here to answer some of your questions about nasal polyps and treatment with DUPIXENT.

Dr. Damask:

When it comes to nasal polyps, typically they’re treated with saline irrigation, topical steroids, and/or oral steroids.

Sometimes we may perform surgery to remove polyps.

But surgery doesn’t treat the underlying cause of inflammation and polyps may come back.

I often prescribe my patients a biologic treatment like DUPIXENT as an add-on maintenance treatment for uncontrolled CRSwNP.

DUPIXENT works to target an underlying source of inflammation and can decrease the size of polyps to help people breathe easier.

Before starting DUPIXENT, you should talk to your doctor about all the medical conditions you have and all the medications you are taking.

You and your doctor should also discuss the potential benefits and risks of treatment, including the most common side effects such as injection site reactions…

…and some serious side effects including allergic reactions that can sometimes be severe, eye problems, inflammation of your blood vessels, and joint aches and pain.

Dr. Damask:

Typically, when I speak with my patients, I like to use the shared decision-making process. I explain the different possible treatment options, as well as the benefits and risks of each.

Then, I have a conversation with them about their treatment goals and what will best fit their needs and lifestyle.

This is important to me; I want to make sure that my patient has the right treatment option for them.

When I’m specifically prescribing DUPIXENT, I make sure my patients are comfortable with the idea of an injection every two weeks.

I explain the clinical information and I let them know that I’m here to support them.

Let’s take a look at the next question.

Dr. Damask:

I discuss with my patients all appropriate treatment options that might work for them. I want my patients to know that they have choices and that I’m here to help them make their decision. When appropriate, we discuss DUPIXENT as a one of those treatment options.

Let’s check out the next question.

Dr. Damask:

When it comes to DUPIXENT my patients and I have been happy with the results we’ve seen.

When my patients come in for checkups a few weeks after they’ve started DUPIXENT, I can actually see that their nasal polyps have gotten smaller.

Many of my patients with smell improvement come back and tell me they didn’t realize how much their loss of smell had really affected them prior to starting DUPIXENT.

I love to hear stories about how they can smell their loved ones’ cooking again.

In clinical trials, patients have seen results in as little as two to four weeks.

I always look forward to seeing my patients after they've been on DUPIXENT for a few months and hearing how their symptoms have improved.

Important Safety Information
and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have CRSwNP and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, or a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with chronic rhinosinusitis with nasal polyposis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, high count of a certain white blood cell (eosinophilia), trouble sleeping (insomnia), toothache, gastritis and joint pain (arthralgia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider.

Please see accompanying full Prescribing Information including Patient Information.


DUPIXENT is a prescription medicine used with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with chronic rhinosinusitis with nasal polyposis under 18 years of age.

Why Partner with a Specialist Who Treats Nasal Polyps? 

CRSwNP specialists perform a series of tests to determine if you have loss of smell and also the extent if needed.

Some specialists may use a camera to see inside the nasal cavity to understand if you have nasal polyps and inflammation.

Working with a specialist can help create a personalized treatment plan to help manage the symptoms and severity of your nasal polyps.

Find a Nearby Specialist Who Treats Nasal Polyps 

Use this Healthgrades™ tool to easily find nearby specialists with experience in treating adults with uncontrolled chronic rhinosinusitis with nasal polyposis (CRSwNP).

Ready to HAVE A productive CONVERSATION
WITH YOUR specialist?

Use our doctor discussion guide to have a successful conversation with your doctor about:

  • CRSwNP symptoms
  • Symptom frequency and severity
  • Treatment goals
  • How DUPIXENT works