About Nasal Polyps

THE LATEST SCIENCE. PROVEN RESULTS.

It is now known that nasal polyps may be caused by an underlying inflammation called type 2 inflammation.

While surgery removes nasal polyps and improves symptoms, surgery may not treat an underlying cause of nasal polyps, which means nasal polyps may grow back and you could need surgery again.

DUPIXENT MAY BE AN OPTION FOR YOU

If you don't feel like your condition is controlled, take the opportunity to learn more about DUPIXENT and fill out our discussion guide to talk with your doctor about whether DUPIXENT is an option for you.


Also, be sure to visit the Results With DUPIXENT page to see what benefits were found in 2 clinical trials.

View the Results
Back

ARE YOUR NASAL POLYPS UNDER CONTROL?

Have you experienced any of the below with
your nasal polyps?

Nasal congestion
Reduced sense of smell
Nasal polyp regrowth after surgery
Oral steroid use

Does any of this sound familiar?

Yes, it Does

TAKING A BIOLOGIC

Still unsure about taking a biologic? Hear from a DUPIXENT
patient who also had her doubts, but after talking with her
doctor decided to give it a try.

Transcript

VO:

DUPIXENT® is a prescription medicine used with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with chronic rhinosinusitis with nasal polyposis under 18 years of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information.

Individual results with DUPIXENT may vary.

Kathy:

Hi, I’m Kathy.

When my doctor encouraged me to try a biologic treatment for my uncontrolled nasal polyps, I was hesitant.

I don’t know... There was something about the idea of a “biologic” that seemed weird to me. I didn’t understand what it was or how it would work inside my body.

I had tried multiple prescription treatments—steroids, pills, nasal sprays. I’d even had surgery. Those options made more sense to me.

A biologic was something different and unfamiliar.

Still, I knew I needed to control my nasal polyps. I talked to my doctor about biologics and did some research, and I eventually came around.

I learned that a biologic can target underlying sources of inflammation, like the kind that causes my nasal polyps.

I talked with my doctor, and he reassured me that he had other patients on biologic treatments who had seen positive results and thought I might as well.

That made me feel more at ease.

At the end of the day, I decided to move forward with adding a biologic treatment.

And, in my case, that treatment was DUPIXENT.

Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.

My doctor and I talked about the potential benefits and risks of treatment including the most common side effects such as injection site reactions, and some serious side effects such as allergic reactions, including anaphylaxis, eye problems, and inflammation of your blood vessels.

I’m happy to say that with DUPIXENT my nasal polyps are under control.

Looking back, I wish I would have started treatment sooner!

My advice? Do your homework, talk to your doctor, and see if DUPIXENT is right for you.

Thanks for watching!

VO:

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
    • There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have CRSwNP and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.

The most common side effects in patients with chronic rhinosinusitis with nasal polyposis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, high count of a certain white blood cell (eosinophilia), trouble sleeping (insomnia), toothache, gastritis and joint pain (arthralgia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with chronic rhinosinusitis with nasal polyposis under 18 years of age.