DUPIXENT is a prescription medicine used as an add-on maintenance treatment in adults and children 6 years of age and older who have moderate-to-severe eosinophilic or oral steroid dependent asthma that is not controlled with their current asthma medicines. DUPIXENT is not used to treat sudden breathing problems and will not replace an inhaled rescue medicine.
For uncontrolled moderate-to-severe eosinophilic or OCS-dependent asthma
Pre-filled Pen
Pre-filled Syringe
Administer the
subcutaneous
injection into the:
OUTER UPPER ARMS
only if a caregiver is
administering injection
ABDOMEN
except for the
2 inches around the navel
THIGHS
If your dosing schedule gets off track, follow these instructions:
Get live assistance online, over the phone, or in person
DUPIXENT MyWay® Nurse Educators can provide you with supplemental injection training in person, virtually, or by phone. This training can be coordinated through your DUPIXENT Case Manager by calling 1-844-DUPIXENT (1-844-387-4936), Option 1.
Please note that your first injection training will need to come from your doctor’s office.
| Initial Dose |
Subsequent Doses |
|---|---|
| 600 mg (2 x 300 mg injections) | 300 mg Every 2 weeks |
| OR | |
| 400 mg (2 x 300 mg injections) | 200 mg Every 2 weeks |
| Dosage for patients with oral steroid-dependent asthma or with co-morbid moderate-to-severe eczema, chronic rhinosinusitis with nasal polyps, or allergic fungal rhinosinusitis* | |
| 600 mg (2 x 300 mg injections) | 300 mg Every 2 weeks |
*For pediatric patients 12 years to 17 years of age (≥60 kg) and adults with allergic fungal rhinosinusitis.
| Recommended Dosagea | |
|---|---|
| 66 lb or more | 200 mg Every 2 weeks |
| 33 lb to <66 lb | 300 mg Every 2 weeks |
aFor children (6 years-11 years of age) with asthma, no initial loading dose is recommended.
For children (6 years-11 years of age) with asthma and co-morbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients (ages 6 years-17 years) with eczema, which includes an initial loading dose.
If your dose schedule is every 4 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, start a new every-4-week dose schedule from the time you remember to take your DUPIXENT injection.
If your dose schedule is every 2 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose exceeds 7 days, start a new every-2-week dose schedule from the time you remember to take your injection.
No, you should always follow your healthcare provider’s instructions for dosing and how to give injections.
| Initial Dose | Subsequent Doses |
|---|---|
| Adults, pediatric patients (12+ years) |
|
| 400 mg; two 200-mg injections |
200 mg every 2 weeks |
| OR | |
| 600 mg; two 300-mg injections |
300 mg every 2 weeks |
| Patients with oral steroid–dependent asthma or with co-morbid moderate-to-severe eczema, chronic rhinosinusitis with nasal polyps, or allergic fungal rhinosinusitis* |
|
| 600 mg; two 300-mg injections |
300 mg every 2 weeks |
*For pediatric patients 12 years to 17 years of age (≥60 kg) and adults with allergic fungal rhinosinusitis.
| Recommended Dosagea |
|---|
| Body weight 33 lb to under 66 lb |
| 300 mg every 4 weeks |
| 66 lb or more |
| 200 mg every 2 weeks |
aFor children 6 years-11 years of age with asthma, no
initial loading dose is recommended.
For pediatric patients 6 years-11 years years old with asthma and co-morbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients 6 years-17 years with eczema, which includes an initial loading dose.
Talk to your healthcare provider and see the detailed Instructions for Use that come with DUPIXENT for information on how to prepare and inject DUPIXENT and how to properly store and throw away (dispose of) used DUPIXENT Pre-filled Syringes or DUPIXENT Pre-filled Pens prior to taking the drug. The DUPIXENT Pre-filled Pen is only for use in adults and children 6 years of age and older.
DUPIXENT is a biologic—an injectable type of medication that is processed in the body differently than oral medications (pills) or steroids. Today, different biologics are used to treat many conditions you may be familiar with.
