Although the cause of prurigo nodularis (PN) is not entirely understood, it is thought to begin inside the body, where an abnormal relationship between the skin, nervous system, and immune system can lead to inflammation.
Inflammation results in the signs and symptoms you see and feel, like unrelenting itch.
This unrelenting itch leads to scratching and the development of itchy bumps over time, resulting in more scratching and rubbing. Chronic scratching can lead to scarring.
PN is an uncommon chronic inflammatory skin disease that primarily affects adults. Signs and symptoms include itch lasting 6 weeks or longer, a history of repeated scratching, picking, or rubbing of the skin, and the presence of bumps.
While the symptoms may be similar, PN can appear differently depending on the color of your skin. Explore the PN Skin Gallery to see prurigo nodularis on a wide range of skin tones.
It’s time to clear up some misconceptions about PN. Watch a real DUPIXENT patient share facts about this condition.