Our goal is for you or your loved one to get the most out of your visit to the doctor—whether you’re just beginning your
treatment journey or looking for a way to manage your prurigo nodularis (PN).

Answer the questions in this form and create your own personalized guide. You can use it to help start a
conversation with your doctor to see if DUPIXENT may be right for you.

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  • Personal Info
  • Journey
  • Symptom Assessment
  • Impact
  • Review

If you have PN, then you know living with the pain, bumps, and intense, relentless itch can be challenging. But you should know there may be a treatment option for you. DUPIXENT is the first FDA-approved treatment for adults with PN. If you are currently experiencing PN symptoms, use this guide to share your experience with your skin specialist and ask if DUPIXENT may be right for you. Please remember that your healthcare provider is your best source of information and to always make decisions in consultation with your healthcare provider.



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Please remember that this is intended to be a helpful way for you to prepare for your conversation with your provider, but should not replace a full conversation with your provider.


Let’s set an appointment on your calendar to remind you of your next doctor’s visit. It will include a link to your personalized discussion guide for easy reference, which will help you have a productive conversation with your doctor.

Symptom Frequency







Condition Description

Symptom Intensity






Treatment Goal


DUPIXENT is a prescription medicine used to treat adults with prurigo nodularis (PN). It is not known if DUPIXENT is safe and effective in children with prurigo nodularis under 18 years of age.

Next Steps


  • How does DUPIXENT work?
  • How would I take DUPIXENT?
  • How do I get started with DUPIXENT?
  • What are the possible side effects of DUPIXENT?
  • How can DUPIXENT help treat my PN?


Add any additional notes to discuss with your doctor.

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with asthma include injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

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DUPIXENT® and DUPIXENT MyWay® are registered trademarks of Sanofi Biotechnology.
DUP.23.01.0270     Last Update: June 2023