Being unfamiliar with injections or having questions around taking DUPIXENT is normal. That’s why we’ve provided resources to help after you've been trained by your healthcare provider. Watch videos on how to take DUPIXENT, hear from real patients about the injection process, and get tips and answers to frequently asked questions. And remember, it is always important to talk to your doctor.
Use DUPIXENT exactly as prescribed by your doctor. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is available as a single-dose pre-filled syringe (200 mg or 300 mg) with needle shield or pre-filled pen (300 mg).
Select the correct option below to see the supplemental injection training video and download the Instructions for Use that match how you take DUPIXENT.
The caregiver video features a caregiver injecting an adolescent patient. DUPIXENT is not approved for patients under 18 years of age with chronic rhinosinusitis with nasal polyposis.
Hi there. I'm Laura.
Today I'm going to show you how to properly self-inject a dose of DUPIXENT (dupilumab).
You've already learned how to self-inject with your healthcare provider.
I'm here to guide your first at-home experience.
When I first started self-injections, I found syringes really intimidating. I've gotten better at the process since then, so I want to share those steps with you today.
I'll show you: what supplies to gather, how to prep the injection area, and how to inject the dose and discard your used syringe.
If you haven't yet read the instructions for use located in your treatment packaging, pause the video and take a look.
I found it helpful to understand the plunger, syringe body, and needle cap before handling the syringe itself.
Contact your healthcare provider or the DUPIXENT MyWay® Hotline with any questions.
It's time for me to take my DUPIXENT injection. Feel free to watch me and follow along as I self-inject.
Narration
Take your medication out of the refrigerator. Never freeze your syringe.
Remove the syringe by holding the middle of the syringe body.
Your DUPIXENT pre-filled syringe may appear different than what I am using in this video, based on the prescribed dose. If you have questions about the dosage prescribed to you, please contact your healthcare provider.
Check the label to make sure the medication inside is correct and the expiration date has not passed. If it isn't right, contact your pharmacy.
You may see an air bubble, this is normal. Do not try to get rid of any air bubbles.
The liquid inside should be clear, and colorless to pale yellow.
Do not use the syringe if the liquid is discolored or cloudy, or if it contains visible flakes or particles. Throw away, dispose of, the used DUPIXENT single-dose pre-filled syringe right away after use.
If you have any questions about whether the syringe is okay to use, please call the DUPIXENT MyWay Hotline, or your healthcare provider.
Lay the syringe on a flat surface and let it naturally warm to room temperature.
The recommended warming time for the 200mg syringe is 30 minutes, and for the 300mg syringe, it's 45 minutes.
While you wait, gather the additional materials necessary to self-inject.
You need one cotton ball or gauze, one alcohol wipe, and a puncture resistant Sharps Disposal Container.
If you don't have a Sharps Disposal Container, call a DUPIXENT MyWay representative to request a complimentary Sharps Disposal Container.
Now, take your supplies to an area where you can sit comfortably.
When you are ready to get started, wash your hands thoroughly.
Choose your injection site. Both the stomach and thigh are acceptable, except for the two inches around your belly button.
If a caregiver gives you the injection, the outer area of the upper arm is also an option. The person giving the injection should follow the same preparation procedure.
Be sure to choose a different site each time you inject DUPIXENT.
Clean your skin with the alcohol wipe.
Do not touch the injection site again or blow on it before the injection. Let your skin dry before injection.
Hold the DUPIXENT syringe in the middle of the Syringe Body with the Needle pointing away from you and carefully remove the cap from the syringe.
Pinch a fold of skin at the injection site. Pinching your skin helps the medicine go into a fatty layer, just below the skin, and not into the muscle.
Take a deep breath.
Continue to pinch, as you insert the needle completely at about a 45° angle.
Relax your pinch.
Push the plunger down slowly and steadily as far as it will go, until the syringe is empty.
You will feel some resistance. This is normal.
Lift your thumb to release the Plunger Rod until the Needle is covered by the Needle Shield and then remove the Syringe from the injection site.
Lightly press a cotton ball or gauze on the injection site if you see any blood. Do not put the Needle Cap back on.
Do not rub your skin after the injection.
You can also cover the site with a bandage.
Put your used Needles, DUPIXENT Syringes, and Needle Caps in a FDA-cleared Sharps Disposal Container right away after Use.
Do not dispose of needles, DUPIXENT Syringes, and Needle Caps in your household trash.
Follow your local guidelines and ask your healthcare provider for the appropriate way to dispose of the container once it is full.
Do not recycle your used Sharps Disposal Container.
Do not reuse the syringe.
If you would like to practice before doing the actual injection and you have received the DUPIXENT training kit from your doctor's office, you can practice the 45° injection angle with your training syringe and the angle aid, and you could always watch the video again.
Remember, do not use the angle-aid to administer an actual injection.
Narration - On Camera Ending
Be sure to keep track of your injection date and site.
Thank you for joining me today. Remember, you can re-watch this video as often as you like to refresh your memory.
Contact your healthcare provider or the DUPIXENT MyWay Hotline with any questions or concerns.
Narration - ISI Indication
MOM: Since you’re watching this video, I know you’ve already learned how to give an injection with your healthcare provider. I’m just here to help guide you through your first at-home experience.
When I first started giving injections, I found syringes really intimidating. I've gotten better at the process since then, so I wanted to share those steps with you today.
If you haven’t yet read the Instructions for Use located in your treatment packaging, pause the video and take a look. And if you have any questions along the way, don’t hesitate to reach out to your healthcare provider or the DUPIXENT MyWay hotline. They’re always there to help.
MOM: Are you ready? …OK
Are you ready?
SON: What?
MOM: Let’s show them how to properly inject a dose of DUPIXENT.
SON: Oh, sure.
MOM: First, take your medication out of the refrigerator. Never freeze your syringe.
Remove the syringe by holding the middle of the syringe body.
A few things to remember:
Your DUPIXENT pre-filled syringe may appear different from what you see in this video, based on the prescribed dose. If you have questions about the dosage prescribed, please contact your healthcare provider.
OK, now it’s time to check the label to make sure the medication and dosage are correct and the expiration date has not passed. If it isn’t right, contact your pharmacy.
SON: Looks right to me.
MOM: Yup.
Now look at the medicine through the Viewing Window on the DUPIXENT syringe. The liquid inside should be clear and colorless to pale yellow. You may see an air bubble; this is normal. Do not try to get rid of any air bubbles.
Do not use the syringe if the liquid is discolored or cloudy, or if it contains visible flakes or particles.
Throw away, dispose of, the used DUPIXENT single-dose, pre-filled syringe right away after use.
If you have any questions about whether the syringe is OK to use, please call the DUPIXENT MyWay® hotline, or your healthcare provider.
Lay the syringe on a flat surface and let it naturally warm to room temperature. The recommended warming time for the 200mg syringe is 30 minutes, and for the 300mg syringe it's 45 minutes.
Here are a few more things to remember:
While you wait, gather the additional necessary materials.
You need one cotton ball or gauze.
SON: Check.
MOM: One alcohol wipe.
SON: Check.
MOM: And a puncture-resistant sharps disposal container.
SON: Check.
MOM: If you don’t have a sharps disposal container, call a DUPIXENT MyWay representative to request a complimentary sharps disposal container.
When you are ready to get started, wash your hands thoroughly.
Now, take your supplies to an area where you can sit comfortably.
Choose your injection site. Both the stomach and thigh are acceptable, except for the two inches around the belly button. The outer area of the upper arm is also an option since you are giving the injection to someone, but not if you’re self-injecting.
Be sure to choose a different site each time you inject DUPIXENT.
OK, now clean the skin with the alcohol wipe.
Do not touch the injection site again or blow on it before the injection.
Once the skin is dry, hold the DUPIXENT syringe in the middle of the syringe body with the needle pointing away from you and carefully remove the cap from the syringe.
Pinch a fold of skin at the injection site. Pinching the skin helps the medicine go into a fatty layer, just below the skin, and not into the muscle.
Take a deep breath.
Continue to pinch as you insert the needle completely at about a 45° angle.
Relax your pinch.
Push the plunger down slowly and steadily as far as it will go, until the syringe is empty. You will feel some resistance. This is normal.
Lift your thumb to release the plunger rod until the needle is covered by the needle shield and then remove the syringe from the injection site.
Lightly press a cotton ball or gauze on the injection site if you see any blood. Do not put the needle cap back on, and do not rub the skin after the injection.
SON: Got it.
MOM: You can also cover the site with a bandage.
OK, now put the used DUPIXENT syringe and cap in an FDA-cleared sharps disposal container right away after use.
Do not put DUPIXENT syringes in your household trash. Follow your local guidelines and ask your healthcare provider for the appropriate way to dispose of the container once it is full.
Do not recycle your used sharps disposal container. And do not reuse the syringe.
If you would like to practice before doing the actual injection and you have received the DUPIXENT training kit from your doctor's office, you can practice the 45° injection angle with the training syringe and the angle aid. Do not use the angle aid to administer an actual injection.
Finally, always be sure to keep track of the injection date and site.
Well, now you know how to give a dose of DUPIXENT. If you follow these steps, you’ll be a pro in no time.
Feel free to rewatch this video as many times as you’d like. And again, reach out to your healthcare provider or call the DUPIXENT MyWay hotline if you have any questions.
Well, that wasn’t so bad, was it?
SON: What?
Remove the DUPIXENT Syringe from the carton by holding the middle of the Syringe Body.
Ensure you have the following:
*Items not included in the carton
When you receive your DUPIXENT Syringes, always check to see that:
Lay the DUPIXENT Syringe on a flat surface and let it naturally warm to room temperature for at least 45 minutes for 300 mg dose or 30 minutes for 200 mg dose.
Pinch a fold of skin at the injection site (thigh or stomach, except 2 inches around your belly button, or outer area of the upper arm if injected by your caregiver). The figure shows an example of pinching a fold of skin on your stomach.
Tom:
Hey, I’m Tom. Thanks for watching. Today I’m going to show you how to properly self-inject a dose of DUPIXENT (dupilumab), using the single-dose pre-filled pen.
Since you’ve already learned how to self-inject with your healthcare provider, I’ll be here to guide your through your first at-home experience.
To some, self-injections can be intimidating. I was nervous when I first started, but with some practice and help from my healthcare provider, I’ve gotten much better at the process, and I want to share those steps with you, today.
First thing we’ll go over is: What supplies to gather, How to prep the injection area, and How to inject the dose and discard your single-use, pre-filled pen.
If you haven’t yet read the instructions for use located in your DUPIXENT treatment packaging, pause the video and take a look. Please read all the instructions carefully, before using the pre-filled pen.
VO:
Let’s take a closer look at the pre-filled pen. I found it helpful to review the different parts of the pre-filled pen, like the cap, the window and the needle cover, before handling the pre-filled pen itself.
Contact your healthcare provider or the DUPIXENT MyWay Hotline with questions. They’re always there to help.
Tom:
Ok, it’s time for me to take my DUPIXENT Injection. Feel free to watch me as I self-inject.
VO:
To begin, take your medication out of the refrigerator.
Take one pen out of the packaging by holding the middle of the pen body.
Now, let’s check the label on the pen to ensure that the medication and dosage strength are correct and the expiration date has not passed.
Do not use the pen if the expiration date has passed. If the dosage strength or expiration date isn’t right, contact your pharmacy.
Next, take a look at the medicine through the viewing window. The liquid inside should be clear and colorless, to pale yellow. You may see an air bubble. This is totally normal.
If you have any questions about whether the pen is okay to use, please call the DUPIXENT MyWay Hotline or your healthcare provider.
If you have an unused pre-filled pen, return it to the refrigerator in the original carton to protect it from light.
Lay the pre-filled pen on a flat surface and let it naturally warm to room temperature.
The recommended warming time for the 300mg pen is 45 minutes.
As the pen warms up, let’s gather some additional materials you’ll need to self-inject. You’ll need a cotton ball or gauze, an alcohol wipe, and a puncture resistant Sharps Disposal Container.
If you don’t have a Sharps disposal container, call a DUPIXENT MyWay representative to request a complimentary Sharps disposal Container.
If you don’t have a puncture resistant disposal container, call your pharmacy, healthcare provider, or DUPIXENT patient support to request a puncture resistant disposal container.
We’re almost ready to inject DUPIXENT.
First, let’s wash our hands thoroughly with soap and water.
Now, take your supplies to an area where you can sit comfortably. I prefer the comfort of my living room couch, you might prefer the bathroom, or your bedroom for privacy.
Next, let’s choose an injection site. Both the stomach and thigh are acceptable, except for the 5 cm [OR 2 in] around your belly button.
If a caregiver gives you the injection, the outer area of the upper arm is also an option. The person giving the injection should follow the same preparation procedure.
Be sure to choose a different site each time you inject DUPIXENT.
Now, clean your skin with the alcohol wipe.
Do not touch the injection site again or blow on it before the injection.
Let your skin dry before injection.
Pick up the pen by holding the middle of the pen body with the needle pointing away from you. With your other hand, pull the cap straight off. Once you have removed the cap, do not put it back on.
Place the needle cover on your skin at approximately a 90-degree angle. Make sure you can see the injector window.
Press down and hold the pen firmly against your skin until you can no longer see the needle cover. There will be a “click” when the injection starts.
As you hold the pen firmly against your skin, the injector window will start to turn yellow. The injection can take up to 20 seconds.
You may hear a second “click”. Check to see if the entire window has turned yellow before removing the pen. Slowly count to 5 and then lift the pen straight up off the skin.
That’s it!
If the window does not turn fully yellow, remove the pen and call your healthcare provider. Do not give yourself a second dose without speaking to your healthcare provider.
Lightly press a cotton ball or gauze on the injection site if you see any blood. You can also cover the site with a bandage. If the bleeding doesn’t stop, contact your healthcare provider.
Be sure to put the used pen and its cap into a puncture-resistant Sharps Disposal Container right away after use.
Follow your local guidelines and ask your healthcare provider for the appropriate way to dispose of the container once it is full.
Be sure to keep track of your injection date and site.
Tom:
Thank you for joining me today. Remember, you can re-watch this video as often as you like to refresh your memory.
Contact your healthcare provider or the DUPIXENT MyWay Hotline with any questions or concerns.
To Camera:
Mom: Hi there. Thanks for watching. Today we’re going to show you how to properly inject a dose DUPIXENT (dupilumab), using the single-dose pre-filled pen. Since you’ve already learned how to self-inject with your healthcare provider, we’re here to guide your through your first at-home experience. When I first started giving injections, I found it intimidating, but with a little practice and help from our healthcare provider, I’ve gotten much better at the process, and I want to share these steps with you, today.
First thing we’ll go over is: What supplies to gather, How to prep the injection area, and How to inject the dose and discard your single-dose pre-filled pen. If you haven’t yet read the instructions for use located in your DUPIXENT treatment package, pause the video and take a look. Please read all the instructions carefully, before using the pre-filled pen.
VO:Let’s take a closer look at the pre-filled pen. I found it helpful to review the different parts of the pre-filled pen, like the cap, the window and the needle cover, before handling the pre-filled pen itself.
Contact your healthcare provider or the DUPIXENT MyWay Hotline with questions. They’re always there to help.
To Camera:
Mom:Ok, it’s time for your DUPIXENT injection. Are you ready?
Daughter: Yeah.
VO: To begin, take your medication out of the refrigerator.
Take one pen out of the packaging by holding the middle of the pen body. Now, let’s check the label on the pen to ensure that the medication and dosage strengths are correct and the expiration date has not passed. Do not use the pen if the expiration date has passed. If the dosage strength or expiration date isn’t right, contact your pharmacy. Next, take a look at the medicine through the viewing window. The liquid inside should be clear and colorless, to pale yellow. You may see an air bubble. This is totally normal.
If you have any questions about whether the pen is okay to use, please call the DUPIXENT MyWay Hotline or your healthcare provider. If you have an unused pre-filled pen, return it to the refrigerator in the original carton to protect it from light.
Lay the pre-filled pen on a flat surface and let it naturally warm to a room temperature of less than 77°F.
The recommended warming time for the 300mg pen is 45 minutes.
Throw away any used pre-filled pen that has been left at room temperature for more than 14 days.
As the pen warms up, let’s gather some additional materials you’ll need to inject. You’ll need a cotton ball or gauze, an alcohol wipe, and a puncture resistant sharps disposal container.
If you don’t have a sharps disposal container, call a DUPIXENT MyWay representative to request a complimentary sharps disposal container.
We’re almost ready to inject DUPIXENT.
First, let’s wash our hands thoroughly with soap and water.
Now, take your supplies to an area where you can sit comfortably. I prefer the comfort of our living room couch, you might prefer the bathroom, or your bedroom for privacy.
Next, let’s choose an injection site. Both the stomach and thigh are acceptable, except for the 5 cm [OR 2 in] around your belly button.
The outer area of the upper arm is also an option since you are giving the injection to someone, but not if you are self-injecting.
Be sure to choose a different site each time you inject DUPIXENT.
Now, clean the skin with the alcohol wipe.
Do not touch the injection site again or blow on it before the injection. Let your skin dry before injection.
Pick up the pen by holding the middle of the pen body with the needle pointing away from you. With your other hand, pull the cap straight off.
Once you have removed the cap, do not put it back on.
Place the needle cover on the skin at approximately a 90-degree angle. Make sure you can see the injector window.
Press down and hold the pen firmly against the skin until you can no longer see the needle cover. There will be a “click” when the injection starts.
As you hold the pen firmly against the skin, the injector window will start to turn yellow. The injection can take up to 20 seconds.
That’s it!
If the window does not turn fully yellow, remove the pen and call your healthcare provider. Do not give a second dose without speaking to your healthcare provider.
Lightly press a cotton ball or gauze on the injection site if you see any blood. You can also cover the site with a bandage. If the bleeding doesn’t stop, contact your healthcare provider.
Be sure to put the used pen and its cap into a puncture-resistant sharps disposal container right away after use.
Follow your local guidelines and ask your pharmacy or healthcare provider for the appropriate way to dispose of your used pen.
Be sure to keep track of your injection date and site.
To Camera:
Thank you for joining us today.
Remember, you can re-watch this video as often as you like to refresh your memory.
Contact your healthcare provider or the DUPIXENT MyWay Hotline with questions.
Find a clean, flat work surface. Make sure you have the following supplies:
* Items not included in the carton
Lay the DUPIXENT Pre-filled Pen on a flat surface and let it naturally warm up at room temperature less than 77°F (25°C) for at least 45 minutes.
This Instructions for Use has been approved by the U.S. Food and Drug Administration.
For more information on dosing, select your indication below.
Watch patients talk about being more
comfortable with injections
Transcript
VO: DUPIXENT is a prescription medicine used:
Important Safety Information
Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.
Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information
Before starting DUPIXENT, you should talk to your doctor about all the medical conditions you have and medications you are taking. You and your doctor should also discuss the potential benefits and risks of treatment with DUPIXENT including the most common side effects such as injection site reactions, and some serious side effects such as allergic reactions including anaphylaxis, eye problems and inflammation of your blood vessels.
JENNIFER: My doctor explained that I would give myself an injection once every two weeks. And explained to me that it works from within the body, as opposed to the other creams and lotions and things that I was putting on my skin.
ANTHONY: When I heard DUPIXENT was an injection I was concerned on how I would handle injections and doing it myself.
DUPIXENT MyWay sent a nurse to my house to show me how to properly self-inject, because of that, I feel more comfortable.
SUE: I was very grateful for the nurse to come out to my house. I didn’t want to do it the wrong way, but it’s just a learning process.
PAM: My doctor trained my husband and I how to give me the injection. I was a little nervous to give myself an injection, so now my husband gives me the injection.I'm so thankful that I have him to– to do it for me.
DEBBIE: When I first found out that DUPIXENT was an injectable, I was a little leery. My husband went with me to the doctor so that we could both be trained on the proper way to inject it. He did it for several months for me and gave me my injections. My daughter was watching one time and said, “Oh my gosh. Mom, just do it yourself.” So, I did! And I'm just really proud that I could do it because I never thought that I would be a person that could do an injection.
Your healthcare provider has shown you how to administer DUPIXENT and provided additional guidance, such as the need to select a different injection site each time. But are you or your loved one still feeling nervous about injecting?
One way to help reduce nervousness is to simply take time to breathe.
When you’re mindful of the present moment, you allow yourself time to accept your feelings, which may help you to manage those nerves.
*Please always consult the Instructions for Use for more information
DUPIXENT MyWay Nurse Educators are trained to help provide patients with supplemental injection training online, over the phone, or in person with a training kit and practice syringe or practice pen.
Hear from patients about starting DUPIXENT and staying on a consistent treatment schedule,
sign up for
injection reminders, and find ideas for staying on treatment while you are traveling.