Not an Inhaler.
Not a Steroid.

DUPIXENT is something different: the only dual-targeting biologic treatment for moderate-to-severe asthma. It's taken by injection under the skin (subcubtaneous injection). It is taken differently than oral steroids and inhalers.

WHAT YOU SHOULD KNOW

DUPIXENT can be given by your doctor in a clinic or doctor's office, or self-administered at home. If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and
inject DUPIXENT.

  • In addition to the training from your doctor, explore the resources available in the Injection Support Center that may help you become more comfortable with injections.

TWO WAYS TO TAKE DUPIXENT

Pre-filled Pen

  • Hear and see when your dose is being delivered
  • Hidden needle
  • Available in 200 mg and 300 mg dose for patients
    aged 6+ years

Pre-filled Syringe

  • Needle shield for safety
  • Full-dose delivery when plunger is completely depressed
  • Available in 100 mg, 200 mg, and 300 mg dose

RECOMMENDED DOSING FOR DUPIXENT

The recommended dose is specified in the appropriate tables below. Use DUPIXENT exactly as prescribed by your healthcare provider.

Talk to your doctor and download the detailed Instructions for Use for information on how to prepare and inject DUPIXENT and how to properly store and dispose of used DUPIXENT Pre-filled Syringes and Pre-filled Pens. Do not try to inject DUPIXENT until you have been shown the right way by your doctor.

 

The recommended dose of
DUPIXENT for patients 12+ years is:

Initial Dose

Subsequent Doses

Adults, pediatric patients
(12+ years)

400 mg;
two 200‑mg
injections

200 mg
every 2 weeks

600 mg;
two 300‑mg
injections

300 mg
every 2 weeks

Patients with oral-steroid dependent asthma
or with moderate-to-severe atopic dermatitis
or adults with co-morbid chronic rhinosinusitis
with nasal polypsosis

600 mg;
two 300-mg
injections

300 mg
every 2 weeks

The recommended dose of
DUPIXENT for children 6-11 years is:

Initial and Subsequent Doses

Body Weight 33 lb to under 66 lb

100 mg;
every 2 weeks

300 mg
every 4 weeks

66 lb or more

200 mg every 2 weeks

For pediatric patients 6-11 years old with asthma and co-morbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients 6-17 years with eczema.

HOW TO TAKE DUPIXENT

In addition to what you've been shown by your doctor, use the
Injection Support Center to get resources and support materials
for taking—and giving—DUPIXENT.

  • Supplemental injection video tutorials
  • Downloadable Instructions for Use

Plus, get testimonials from real patients and mindful breathing techniques.

Nurse Educators Are Here to Help

In addition to the training from your doctor, a DUPIXENT MyWay® Nurse Educator can provide supplemental injection training, either online, over the phone or in-person with a training kit and syringe for practice.

For more information, dial
1-844-DUPIXENT (1‑844‑387‑4936), option 1
Monday-Friday, 8 am - 9 pm EST

WORRIED ABOUT MISSING A DOSE?

If your dose schedule is every other week and you miss
a dose of DUPIXENT:
Give the DUPIXENT injection within 7
days from the missed dose, then continue with your original
schedule. If the missed dose is not given within 7 days,
wait until the next scheduled dose to give your DUPIXENT injection.

If your dose schedule is every 4 weeks and you miss a dose of
DUPIXENT:
Give the DUPIXENT injection within 7 days from
the missed dose, then continue with your original schedule. If the
missed dose is not given within 7 days, start a new every
4 week dose schedule from the time you remember to take
your DUPIXENT injection.

Get tips to help avoid missing a dose
and stay on track with treatment

 

Transcript

RACHEL: I was a little surprised when I found out that DUPIXENT would require an injection every two weeks. It was different than what I was used to. I was used to taking another pill or using another inhaler. I knew adding DUPIXENT was going to change my routine. It was going to be new, but over time I’ve gotten comfortable with it.

SHARRON: When I found out that DUPIXENT was an injectable, I was okay with it. If there was a chance that it could help get my severe asthma under control, then I was willing to do whatever I needed to do.

RACHEL: My doctor and nurses showed me how to properly self-inject. I am a registered nurse and I give injections at work, but I still needed to learn how to properly inject DUPIXENT myself.

SHARRON: Your doctor will walk you through the injection process. I also watched the video on DUPIXENT.com and followed the instructions.

RACHEL: DUPIXENT comes in a pre-filled syringe or pen and is a subcutaneous injection, which means it goes just underneath the skin.

SHARRON: I appreciate that there’s also a pre-filled pen for patients 12 years and older. I used a pre-filled syringe.

RACHEL: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.

SHARRON: My doctor and I talked about the potential benefits and risks of treatment, including the most common side effects such as injection site reactions and some serious side effects including allergic reactions that can sometimes be severe, inflammation of your blood vessels, and joint aches and pain.

SHARRON: Well early on, my doctor steered me to the patient support program, DUPIXENT MyWay and I’m so glad that he did. They’ve been a great resource and even offered to send a nurse to my home to help with further instruction.

RACHEL: I was really blown away by how much support the DUPIXENT MyWay team provides. You feel that they are in this with you and they’re there to help!

SHARRON: I like to do my self-injection in the evening in a quiet part of the house where I can focus. My routine is to do the self-injection after I’ve gotten out of the shower.

RACHEL: I write DUPIXENT on my calendar at home and in my pocket calendar to help me remember when to take it. I’ve got my self-injection routine down. I’m comfortable with it.

VO:

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with asthma include injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age or older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 6 years of age.