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DUPIXENT Dosing for Asthma

Not an Inhaler.
Not a Steroid.

DUPIXENT is something different: the only dual-targeting biologic treatment for moderate-to-severe asthma. It's taken by injection under the skin (subcutaneous injection). It is taken differently than oral steroids and inhalers.

Only 1 or 2 doses a month.*

*Based on weight and age.

WHAT YOU SHOULD KNOW

DUPIXENT can be given by your doctor
in a clinic
or doctor’s office, or
self-administered at home.

If your healthcare provider decides that you or a caregiver
can give DUPIXENT injections, you or your caregiver should
receive training on the right way to prepare and
inject DUPIXENT.

In addition to the training from your doctor, explore the resources available in the Injection Support Center:

  • Supplemental injection video tutorials
  • Downloadable Instructions for Use
  • Testimonials from real patients
  • Mindful breathing exercises
GET SUPPLEMENTAL
INJECTION SUPPORT

RECOMMENDED DOSING FOR DUPIXENT

For uncontrolled moderate-to-severe eosinophilic or OCS-dependent asthma

  • Use DUPIXENT exactly as prescribed by your healthcare provider
  • Do not try to inject DUPIXENT until you have been shown the right way by your doctor.

The recommended dose of DUPIXENT for adults/teens ages 12+ years is:

 

Initial Dose
600 mg  (2 x 300 mg injections)

Subsequent Doses
EVERY 2 WEEKS   300 mg

Initial Dose
400 mg  (2 x 200 mg injections)

Subsequent Doses
EVERY 2 WEEKS   200 mg

Initial Dose
600 mg  (2 x 300 mg injections)

Subsequent Doses
EVERY 2 WEEKS   300 mg

Patients with oral steroid-dependent asthma or with
moderate-to-severe eczema or adults with co-morbid
chronic rhinosinusitis with nasal polyps

The recommended dose of DUPIXENT for children ages 6-11 years is:

 

Initial and
Subsequent Dosing
66 LB OR MORE

EVERY 2 WEEKS   200 mg

Initial and
Subsequent Dosing
33 LB TO <66 LB

EVERY 4 WEEKS   300 mg

For children (6-11 years) with asthma and comorbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients 6-17 with eczema, which includes an initial loading dose.

TWO WAYS TO TAKE DUPIXENT

Dupixent® (dupilumab) Pre-filled Pen (200 mg or 300 mg) for ages 6+ years

Pre-filled Pen

  • Hear and see when your dose is being delivered
  • Hidden needle
  • Available in 200 mg and 300 mg dose for patients
    aged 6+ years
Dupixent® (dupilumab) Pre-filled Syringe (200 mg, or 300 mg) with needle shield for ages 12+ years

Pre-filled Syringe

  • Needle shield for safety
  • Full-dose delivery when plunger is completely depressed
  • Available in 200 mg and 300 mg dose

How to Administer DUPIXENT

  • In children 6 to less than 12 years old, DUPIXENT should be given by a caregiver.
  • In children 12 years and older, it is recommended that DUPIXENT be administered under the supervision of an adult.
  • For the initial dose, administer each of the 2 injections at different injection sites.
  • Rotate the injection site with each injection. See injection site figure.
  • DO NOT inject DUPIXENT into skin that is tender, damaged, bruised, or scarred.
  • See the Instructions for Use for more detailed instructions on the preparation and administration of DUPIXENT.

Where to Administer DUPIXENT

Administer the subcutaneous
injection into the:

OUTER UPPER ARMS
only if a caregiver is
administering injection

ABDOMEN
except for the
2 inches around the navel

THIGHS

Human body diagram of ideal Dupixent® (dupilumab) administration sites including outer upper arms, abdomen, and thighs

What to do If you
miss a dose

Follow these instructions if your dosing schedule gets off track.

Taking DUPIXENT Every 2 Weeks

  • Give injection within 7 days from the missed dose
  • Keep your original schedule for next dose
  • If missed dose exceeds 7 days, wait until next
    scheduled dose to give your injection

Taking DUPIXENT Every 4 Weeks

  • Give injection within 7 days from the missed dose
  • Keep your original schedule for next dose
  • If missed dose exceeds 7 days, administer the dose
    and restart 4-week schedule based on this date

INJECTION REMINDERS

Set a date on your calendar to remind you to take DUPIXENT as directed by your physician. Just choose the calendar you want below to get started.

What do you want to know about DUPIXENT before talking to your doctor?

Select the best option to receive information to address your specific needs.

Change my answer

The benefits and risks of DUPIXENT have been evaluated in clinical trials for both adults and kids (6+ years).

RESULTS IN
ADULTS/TEENS
(AGES 12+ YEARS)
RESULTS IN CHILDREN
(AGES 6-11 YEARS)

As little as $0 copay may be available, and 99% of patients are commercially insured and approved.

LEARN MORE ABOUT
THE COPAY CARD

We can help you advocate for yourself by creating a personalized discussion guide for a productive conversation with your doctor.

Personalize My
Discussion Guide

NURSE EDUCATORS ARE
HERE TO HELP

Get live assistance online,
over the phone, or in person

In addition to the training from your doctor, DUPIXENT MyWay® Nurse Educators can provide supplemental injection training with a training kit and syringe for practice in a variety of ways.

EXPLORE INJECTION SUPPORT
Dupixent Myway® Logo

For more information, dial
1-844-DUPIXENT (1‑844‑387‑4936),
option 1
Monday-Friday, 8 am-9 pm ET

The DUPIXENT MyWay team
provides the support I need. I feel
like they are in this with me and are
here to help.

Rachel,
Real patient.
Individual results may vary.

frequently asked questions

If your dose schedule is every 4 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, start a new every 4 week dose schedule from the time you remember to take your DUPIXENT injection.

If your dose schedule is every 2 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, wait until the next scheduled dose to give your DUPIXENT injection.

SET UP INJECTION
REMINDERS

No, you should always follow your healthcare provider’s instructions for dosing and how to give injections.

The recommended dose of
DUPIXENT for patients 12+ years is:

The recommended dose of
DUPIXENT for children 6-11 years is:

For pediatric patients 6-11 years old with asthma
and co‑morbid moderate-to-severe eczema, follow
the recommended dosage for pediatric patients
6-17 years with eczema.

Talk to your healthcare provider and see the detailed Instructions for Use that come with DUPIXENT for information on how to prepare and inject DUPIXENT and how to properly store and throw away (dispose of) used DUPIXENT Pre-filled Syringes or DUPIXENT Pre-filled Pens prior to taking the drug. The DUPIXENT Pre-filled Pen is only in use for adults and children 6 years of age and older.

DUPIXENT is a biologic—an injectable type of medication that is processed in the body differently than oral medications (pills) or steroids. Today, different biologics are used to treat many conditions you may be familiar with.