Results with DUPIXENT

Why let Asthma hold you back?

DUPIXENT was studied in 3 clinical trials with 2,888 people 12 years of age and older with moderate-to-severe asthma.

Benefits With Every Breath

Improve lung function so you can breathe better in as little as 2 weeks

Help prevent severe asthma attacks

Can reduce or completely eliminate oral steroids

Asthma Clinical Studies

DUPIXENT significantly improved lung function and helped prevent asthma attacks.

Up to 81% Fewer
Asthma Attacks*†

The benefits and risks of
DUPIXENT were evaluated in 3
clinical studies with 2888 patients.

86% of People Reduced
or Eliminated Their Oral
Steroid Dose

In a study of people
dependent on oral corticosteroids

The most common side effects include injection site reactions, pain in the
throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).

  • *In those with high eosinophil counts (a type of white blood cell).
  • The annual rate of severe asthma attacks was a 0.20 with DUPIXENT 300 mg vs 1.04 with placebo.
  • In a clinical study with DUPIXENT 300 mg + Standard of Care vs 68% with placebo + Standard of Care.

Over time with DUPIXENT, I started to
notice a change. My breathing started to
improve, and I was using my rescue
inhaler less and less.

- Marlena, DUPIXENT MyWay®
Patient Ambassador

Individual results may vary.

Watch Marlena's story

HAVE EFFECTIVE CONVERSATIONS
With Your Doctor

Our goal is for you to get the most out of your visit to the doctor. Download the Doctor Discussion Guide for tips on how to drive a productive conversation, and listen to the audio file for an example conversation.


Get the Doctor Discussion Guide
Download
Patients can take part in treatment decisions. Listen to a patient self-advocate for themselves and DUPIXENT with their doctor.

In about 40 seconds you’re going to hear how a patient and doctor might discuss life with moderate-to-severe asthma that is not well controlled and potential treatment with DUPIXENT® (dupilumab). DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age. Let’s take a listen.

DOCTOR: While your asthma is still uncontrolled, it looks like your symptoms haven’t gotten worse, and your test results are about the same as last time. That’s good. I don’t think we’ll have to change your medications at this point.

PATIENT: OK…but I was hoping to talk to you about how my asthma’s really been affecting me.

DOCTOR: OK, tell me more.

PATIENT: Well, there’s so much I can’t do. Like the other day: I was at a birthday party for a friend [pause] and got winded singing “Happy Birthday.” So, of course, now I’m worried about having issues swimming and keeping up with my family next month when we go on our beach trip.

DOCTOR: Are you taking your asthma medications every day like we discussed?

PATIENT: Yeah, I take them, [pause] but it’s not enough. My chest still gets tight, and I feel like I can’t breathe; I can’t seem to stop having asthma attacks. Is there something else I can try?

DOCTOR: Well, you know, sometimes asthma can be hard to control. But I didn’t know it was having such a big impact on your daily life, so I’m glad you brought it up. There are other medicines we can consider.

PATIENT: Actually, that’s one of the things I wanted to talk to you about. I saw something about this medicine called DUPIXENT. Can you tell me anything about it?

DOCTOR: I do have patients who take DUPIXENT. Some have said it has helped prevent asthma attacks from even happening.

PATIENT: That sounds like what I need.

DOCTOR: Before we make a decision, I’d like to tell you a little more about DUPIXENT. Would that be OK?

PATIENT: Sure.

DOCTOR: DUPIXENT is a subcutaneous injection. So…[patient interrupts]

PATIENT: What does sub…subcutaneous mean?

DOCTOR: It just means under the skin. After the initial injection, you would be giving yourself an injection under the skin every other week. We’ll make sure you’re comfortable with the process before you start at home.

PATIENT: Are there any side effects?

DOCTOR: The most common side effects include injection site reactions, pain in the throat—also called oropharyngeal pain—and cold sores in the mouth or on the lips.

PATIENT: OK.

DOCTOR: So, do you think you’re interested in trying DUPIXENT?

PATIENT: Yes! I’m ready to try something different.

DOCTOR: OK, let’s talk about how to get started. [pause] It’s an add-on medication, so you’ll still need to take your regular asthma medicines.

PATIENT: How will I know DUPIXENT is working?

DOCTOR: Give it at least two weeks. After that you may notice that you can breathe better. You may even be able to reduce or eliminate your use of oral steroids. We’ll schedule a follow-up so I can check your progress.

PATIENT: Thanks. I’m looking forward to doing more.

 

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are taking oral, topical, or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. If you are taking asthma medicines, do not change or stop your asthma medicine without talking to your healthcare provider.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.

The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are taking oral, topical, or inhaled corticosteroid medicines. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. If you are taking asthma medicines, do not change or stop your asthma medicine without talking to your healthcare provider.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, shortness of breath, persistent fever, chest pain, or a feeling of pins and needles or numbness of your arms or legs.

The most common side effects in patients with asthma include injection site reactions, pain in the throat (oropharyngeal pain), and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in people aged 12 years and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 12 years of age.