Frequently Asked
Questions
About DUPIXENT
DUPIXENT is a prescription medication and the first biologic approved to treat people 6 years of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.
Get the factsDUPIXENT works with your body’s immune system to help reduce inflammation contributing to your eczema, which may help reduce your uncontrolled moderate-to-severe eczema (atopic dermatitis) symptoms and may give you noticeably clearer skin.
Please see How Dupixent Worksfor more information
Do not use DUPIXENT if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.
Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
- have eye problems.
- have a parasitic (helminth) infection.
- are scheduled to receive any vaccinations. You should not receive a "live vaccine" if you are treated with DUPIXENT.
- are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn
baby.
- There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
- are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have CRSwNP and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.
The efficacy of DUPIXENT has been studied in 3 well-controlled medical studies with approximately 2,100 adults with uncontrolled moderate-to-severe atopic dermatitis.
- DUPIXENT was evaluated in these studies when taken alone and when taken with topical corticosteroids.
The efficacy of DUPIXENT has been studied in a 16-week well controlled medical study with 251 teens ages 12-17 years with uncontrolled moderate-to-severe atopic dermatitis.
The efficacy of DUPIXENT has been studied in a 16-week well controlled medical study with 367 children ages 6-11 years with uncontrolled severe atopic dermatitis also taking topical corticosteroids.
Patients enrolled in these studies were not well controlled with prescription therapies used on the skin (topical), or could not use topical therapies.
View Results inAdults (Ages 18+)
View Results in
Teens (Ages 12-17)
View Results in
Children (Ages 6-11)
DUPIXENT can cause serious side effects, including:
- Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and go to the nearest hospital emergency room if you get any of the following symptoms:
- Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.
The most common side effects of DUPIXENT include:
- injection site reactions
- eye and eyelid inflammation, including redness, swelling, and itching
- cold sores in your mouth or on your lips
Tell your healthcare provider if you have any side effect that bothers you or that does not go away.
These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about
side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit
www.fda.gov/medwatch, or call 1-800-FDA-1088.Dosing
DUPIXENT is given as an injection under the skin (subcutaneous injection) at different injection sites. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In teens 12 years of age or older, it is recommended that DUPIXENT be administered by or under the supervision of an adult. DUPIXENT Pre-filled Syringe should be given by a caregiver in children 6-11 years of age.
The recommended dose of DUPIXENT is specified in the table below. DUPIXENT can be used with or without topical corticosteroids.
| Age/Body Weight of Patient | Initial Dose | Subsequent Dose |
|---|---|---|
| Adults 18+ | ||
| Any weight | 600 mg; two 300-mg injections | 300 mg every 2 weeks |
| Children and Teens | ||
| 33 lb – 66 lb | 600 mg; two 300-mg injections | 300 mg every 4 weeks |
| 67 lb – 132 lb | 400 mg; two 200-mg injections | 200 mg every 2 weeks |
| 133 lb or more | 600 mg; two 300-mg injections | 300 mg every 2 weeks |
- Your initial dose of DUPIXENT is 2 injections under the skin (subcutaneous injection) at different injection sites. After that, it is taken as 1 injection every 2 weeks or every 4 weeks, depending on your weight at different injection sites. DUPIXENT can be used with or without topical corticosteroids.
- Talk to your healthcare professional and see the detailed Instructions for Use that comes with DUPIXENT for information on how to prepare and inject DUPIXENT and how to properly store and throw away (dispose of) used DUPIXENT Pre-filled Syringes or 300 mg DUPIXENT Pre-filled Pens prior to taking the drug.
Get supplemental injection support after your doctor shows you the right way to take DUPIXENT.
Visit the injectionsupport center
Get the Pre-filled syringe Instructions for use
Get the 300 mg Pre-filled Pen (AGES 12+ YEARS) Instructions for use
DUPIXENT can be injected into the thigh, stomach (except for the 2 inches around the belly button), or outer area of the upper arm (if caregiver injects). A different site should be chosen each time DUPIXENT is injected.
- Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it.
- Follow your healthcare provider's instructions and read the Instructions for Use for full details on preparation, administration, and disposal of your injection.
Get the Pre-filled syringe Instructions for use
Get the 300 mg Pre-filled Pen (AGES 12+ YEARS) Instructions for use
If your dose schedule is every other week and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, wait until the next scheduled dose to give your DUPIXENT injection.
If your dose schedule is every 4 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, start a new every 4 week dose schedule from the time you remember to take your DUPIXENT injection.
Speak with your healthcare provider before making any change to your treatment regimen.
set up injection remindersNo, you should always follow your healthcare provider’s instructions for dosing and how to give injections.
Life on DUPIXENT
There are no known foods you should avoid while taking DUPIXENT. If you suspect a side effect with a particular food while taking DUPIXENT, notify your healthcare provider.
Be sure to speak with your healthcare provider.
DUPIXENT should be refrigerated at 36°F to 46°F in the original carton to protect from light. If necessary, DUPIXENT may be kept at room temperature up to 77°F (25°C) for a maximum of 14 days. Do not store above 77°F (25°C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded.
Do not expose DUPIXENT to heat or direct sunlight.
Do not freeze. Do not shake.
Please refer to the DUPIXENT Instructions for Use for complete storage instructions.
Whether you are traveling or not, it’s important to store the syringes in the original carton to protect them from light.
Store refrigerated at 36°F to 46°F (2°C to 8°C) in the original carton to protect from light. If necessary, pre-filled syringes may be kept at room temperature up to 77°F (25°C) for a maximum of 14 days. Do not store above 77°F (25°C). After removal from the refrigerator, DUPIXENT must be used within 14 days or discarded.
Access and Patient Support
Yes. You can continue to receive injection support from your doctor or our Injection Support Center, or if your doctor decides that you or your caretaker can give injections, your doctor will train you. Do not self-adminster DUPIXENT unless you have been trained by a doctor. Patients enrolled in DUPIXENT MyWay® will also have access to their nurse educator to help with supplemental training.
For more information about DUPIXENT support resources, you can enroll in DUPIXENT MyWay®, a program that can provide:
- Tips and tools to help with your uncontrolled moderate-to-severe eczema (atopic dermatitis).
- Supplemental injection training. Your doctor will show you the proper procedure first and decide whether you can self-inject.
- Financial support for eligible commercially insured patients.
- Assistance with insurance questions.
- Assistance locating a pharmacy that can dispense your DUPIXENT prescription.
Sign up or call a support coordinator at 1-844-DUPIXENT (1-844-387-4936) to learn more.
LEARN ABOUT DUPIXENT MyWayYou can use our Cost and Coverage Tool to learn more about cost information for your insurance situation. For the most accurate information regarding your cost and dispensing of DUPIXENT, speak directly with your insurance provider who knows the details of your plan.
use the cost and coverage toolCertain retail pharmacies or specialty pharmacies can fill your prescription. These pharmacies can:
- Coordinate directly with your doctor.
- Manage the handling and service requirements of specialty drugs.
- Ship your medication directly to your home in a special cooler to help make sure the correct temperature is maintained through the process.
- Stay in contact with you and your doctor throughout the treatment.
Notify your pharmacy. In fact, when you take medications that require refills regularly over time, it’s always good to periodically check that your pharmacy has your most up-to-date insurance information on file. This can help you avoid potential delays in getting your prescription.
Contact 1-844-DUPIXENT (1 844 387 4936) to speak to a DUPIXENT MyWay® Nurse Educator, if you have additional questions.
With the DUPIXENT MyWay Copay Card, eligible, commercially insured patients may pay as little as $0* copay per fill of DUPIXENT (maximum of $13,000 per patient per calendar year) if they meet the eligibility requirements, including:
- Have commercial insurance, including health insurance exchanges, federal employee plans, or state employee plans
- Are a resident of the 50 United States, the District of Columbia, or Puerto Rico
- Are prescribed DUPIXENT for an indication approved by the US Food and Drug Administration
*Approval is not guaranteed. THIS IS NOT INSURANCE. Program has an annual maximum of $13,000. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any state pharmaceutical assistance programs. This program is not valid where prohibited by law, taxed or restricted. DUPIXENT MyWay® reserves the right to rescind, revoke, terminate, or amend this offer, eligibility, and terms of use at any time without notice. Additional terms and conditions apply.
You can request copay reimbursement if:
- Your health plan did not accept your Copay Card
- You paid a copay for DUPIXENT before enrolling in DUPIXENT MyWay® and you meet other program requirements
To apply for reimbursement:
- Download and complete the reimbursement form
- Fax it to 1-908-809-6249, or mail it to the address on the form within 90 days of making your
payment. Be sure to include:
- A copy of the front and back of your DUPIXENT MyWay Copay Card
- The original receipt from your prescription purchase (with amount highlighted)
- Your signature
Please allow 7-10 days to process your request.
get the copay reimbursement form
Email DownloadThrough the Patient Assistance Program, qualified patients who are uninsured or whose insurance does not cover DUPIXENT could receive DUPIXENT at no cost.
Those who may qualify must be at least 18 years of age or older, a resident of the 50 United States, the District of Columbia, or Puerto Rico, and demonstrate a financial need with a total annual adjusted gross income of $100,000 or less.
The DUPIXENT MyWay team will research each patient’s situation and determine eligibility. For more information, call 1-844-DUPIXENT (1-844-387-4936), option 1.