Results They Can See, Results They Can Feel

Caring for your child with uncontrolled moderate-to-severe eczema can be a struggle—especially when you’re
constantly trying to avoid triggers. And although your child may outgrow their eczema, approximately 1 in 5 never do.

DUPIXENT in combination with a topical corticosteroid was studied in a 16-week clinical trial with 367 patients ages
6-11 years with severe eczema not adequately controlled with topical prescription treatments.

More children ages 6-11 years taking DUPIXENT* + a
topical corticosteroid (TCS) saw clearer skin and less itch.

>2XSAW CLEAR OR
ALMOST CLEAR SKIN

30% taking 300 mg dose every 4 weeks + TCS vs 13% on TCS only
39% taking 200 mg dose every 2 weeks + TCS vs 10% on TCS only

~4.5XHAD
LESS ITCH

54% taking 300 mg dose every 4 weeks + TCS vs 12% on TCS only
61% taking 200 mg dose every 2 weeks + TCS vs 13% on TCS only

≥75%Skin Improvement in more
than half of children

75% taking 300 mg dose every 4 weeks + TCS vs 28% on TCS only
75% taking 200 mg dose every 2 weeks + TCS vs 26% on TCS only

Your healthcare provider will tell you how much DUPIXENT to inject and how often.
*After an initial loading dose of 2 injections: children less than 66 lb received 300 mg every 4 weeks; children 66 lb or more received 200 mg every 2 weeks.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

In a different type of study (open-label extension) of children (6 months - 17 years of age) continuing on DUPIXENT long-term
through 1 year, the safety results for children (6-11 years) were consistent with those seen in the adult clinical trials.

View the possible side effects of DUPIXENT in patients with moderate-to-severe eczema (atopic dermatitis).


What You Should Know About the Patients in This Study:

100%
Had severe atopic dermatitis
~8.5 years
Average age
~58%
Average body surface area involvement
~92%
Had at least one other allergic condition

DUPIXENT HELPS HEAL THE LOOK AND FEEL OF SKIN

In a clinical trial for children ages 6-11 years, clearer skin was seen. Use the slider to view before and after results of an actual 10-year-old patient and 9-year-old patient after 16 weeks of treatment with DUPIXENT and a topical steroid in a phase 3 clinical trial. A clinical responder was defined as a patient achieving IGA 0 or 1 (clear or almost clear skin). Individual results may vary.

Click and drag
to see results
Click and drag
to see results

GET DOWN TO THE DETAILS

Expand the boxes below to see more detailed results from the clinical study with patients ages 6-11 years.

 

Results at 16 weeks when DUPIXENT was taken with topical
corticosteroids (TCS) compared to patients ages 6-11 years on
topical corticosteroids only

DUPIXENT 300 mg (less than 66 lb) every 4 weeks + TCS

On topical corticosteroids only

30% saw clear or almost clear skin when DUPIXENT was used with TCS vs 13% on topical corticosteroids only

75% saw at least a 75% skin improvement when DUPIXENT was used with TCS vs 28% on topical corticosteroids only

46% saw at least a 90% skin improvement when DUPIXENT was used with TCS vs 7% on topical corticosteroids only

DUPIXENT 200 mg (66 lb or more) every 2 weeks + TCS

On topical corticosteroids only

39% saw clear or almost clear skin when DUPIXENT was used with TCS vs 10% on topical corticosteroids only

75% saw at least a 75% skin improvement when DUPIXENT was used with TCS vs 26% on topical corticosteroids only

36% saw at least a 90% skin improvement when DUPIXENT was used with TCS vs 8% on topical corticosteroids only

Patients ages 6-11 years experienced itch reduction
while participating in a clinical trial

DUPIXENT 300 mg (less than 66 lb) every 4 weeks + TCS

On topical corticosteroids only

54% had itch reduction at 16 weeks when DUPIXENT was used with TCS vs 12% on topical corticosteroids only
 

DUPIXENT 200 mg (66 lb or more) every 2 weeks + TCS

On topical corticosteroids only

61% had itch reduction at 16 weeks when DUPIXENT was used with TCS vs 13% on topical corticosteroids only
 

One day, Calla came home from
school and said “I didn't
itch as much today,” and it
was a really big moment for her
and for us.

- Jill, caregiver of Calla, pediatric patient
taking DUPIXENT

Individual results may vary.

Find a Specialist Who
Treats Eczema

Use this Healthgrades™ tool to easily find nearby
specialists with experience in treating children, teens,
and adults with uncontrolled moderate-to-severe
eczema (atopic dermatitis).

Sanofi US and Regeneron do not endorse or recommend any particular physician, and search results do not include a comprehensive list of doctors in your area.

Have A PRODUCTIVE Conversation
With Your Doctor

Our goal is for you or your loved one to get the most out of
your visit to the doctor. Fill out our personalized discussion
guide to help yourself have a productive conversation
during your next visit.

 

GET THE SPANISH CAREGIVER
DISCUSSION GUIDE

 

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Go to the How DUPIXENT Is Taken page to learn more about dosing and administration information.

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