DUPIXENT® (dupilumab) Results in Children 6 + Years

Results They Can See,
Results They Can Feel

Caring for your child with uncontrolled moderate-to-severe eczema can be a struggle—especially when you’re
constantly trying to avoid triggers. And although your child may outgrow their eczema, approximately 1 in 5 never do.

DUPIXENT in combination with a topical corticosteroid was studied in a 16-week clinical trial in 367 patients ages
6-11 years with severe eczema not adequately controlled with topical prescription treatments.

In a clinical trial at 16 weeks, more children (aged 6-11 years) receiving DUPIXENT* + a topical
corticosteroid (TCS) saw clearer skin and less itch.

CLEARER skin ~2XSAW CLEAR OR
ALMOST CLEAR SKIN

30% on 300 mg every 4 weeks + TCS
vs 13% on TCS only

39% on 200 mg every 2 weeks + TCS
vs 10% on TCS only

NOTICEABLY LESS ITCH ~4.5XHAD
LESS ITCH

54% on 300 mg every 4 weeks + TCS
vs 12% on TCS only

61% on 200 mg every 2 weeks + TCS
vs 13% on TCS only

PROVEN RESULTS ≥75%Skin Improvement in more
than half of children

75% on 300 mg every 4 weeks + TCS
vs 28% on TCS only

75% on 200 mg every 2 weeks + TCS
vs 26% on TCS only

Your healthcare provider will tell you how much DUPIXENT to inject and how often.

*After an initial loading dose of 2 injections: children less than 66 lb received 300 mg every 4 weeks; children 66 lb or more received 200 mg every 2 weeks.

The most common side effects in patients with eczema include:

Injection site reactions
Eye and eyelid inflammation including redness, swelling,
and itching, sometimes with blurred vision
Cold sores in your mouth or on your lips
High count of a certain white blood cell (eosinophilia)

Long-term safety results for children continuing on DUPIXENT with or without TCS in the pediatric extension study through
1 year were consistent with the adult clinical trials.

View the possible side effects of DUPIXENT in patients with moderate-to-severe eczema (atopic dermatitis).

100%

Had severe atopic
dermatitis

~8.5 years

Average age

~58%

Average body
surface area
involvement

~92%

Had at least 1
other allergic
condition

SEE BEFORE AND AFTER RESULTS IN CHILDREN

In a clinical trial for children ages 6-11 years, clearer skin was seen. Use the slider to view before and after results of an actual 10-
year-old patient and 9-year-old patient after 16 weeks of treatment with DUPIXENT and a topical steroid in a phase 3 clinical trial. A
clinical responder was defined as a patient achieving IGA 0 or 1 (clear or almost clear skin). Individual results may vary.

Click and drag
to see results

I’m really proud of Catch taking
his DUPIXENT injection. At first,
he resisted, but now he sees the
benefits of taking DUPIXENT.

- Amber, DUPIXENT MyWay® Caregiver
and Patient Ambassador
Individual results may vary.

AMBER AND
CATCH'S STORY

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