Video begins. Open on the DUPIXENT 200mg and 300mg Pre-Filled Pens and Packaging displayed on a countertop.
Cut to MAYA, a mother, standing in front of a kitchen counter. A little girl runs quickly past her, a blur across the frame.
To Camera Audio
Audio Hi there! I’m Maya, and you’ll meet my daughter Emily in just a few moments.
We both use DUPIXENT (dupilumab), just like you. And just like you, our doctor showed us how to inject it, but we all need a refresher every once in a while. So we’re going to show you how to properly inject a dose of DUPIXENT. Whether you’re administering the injection to yourself, or injecting a loved one, we’ll be an additional guide for your at-home experience.
- The DUPIXENT pre-filled pen is approved for patients 2+ years of age.
I know injections can be intimidating. To be honest, we were both pretty nervous when we first learned that we’d be doing the injections ourselves, at home. But with a little patience, practice, and a few support calls to our doctor and DUPIXENT MYWAY, we’ve gotten better at the process, and are excited to share that with you.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“When I heard DUPIXENT was an injection, I was concerned on how I would handle the injections and doing it myself.” (3:12-3:20 from DUP_Video Booth_Self Injection_v18_HI RES)
“Over time I’ve definitely gotten more used to taking DUPIXENT. It’s a part of my life, just like going to the doctor.” (2:21 - 2:29 from DUP_CRM_Taking DUP_12 Hi Res)
“At first my daughter Jolene wasn't thrilled at the idea of receiving an injectable medication so we sat down and we talked about and we weighed our options. Jolene thought about it and she said ``you know what mommy, I really want to try DUPIXENT, let's move forward.”” (DUP PEDS AD_Injection_FINAL_10.23.2020 1:10 - 1:26)
Cut to Maya in the kitchen. She holds up finger for each corresponding step below (1, 2, 3).
To Camera Audio
So we follow three basic steps for either self-injecting, or giving an injection to someone. I’ll give you the important details later in this video, but here are the basics.
One - Gather your materials. You’ll need things like your DUPIXENT pre-filled pen, an alcohol wipe, a cotton ball or gauze, and your Sharps disposal container.
Two – Prep. This includes cleaning the injection site really well with the alcohol wipe.
And Three - inject and dispose of the single-dose, pre-filled pen. In my opinion, this could be the most intimidating part of the injection process, but don’t worry. We’re here for you.
Maya walks over to the kitchen island counter and picks up the DUPIXENT Instructions for use.
Before we do any of that though it’s important to read the “Instructions for Use” located in your DUPIXENT treatment packaging. If you haven’t read it yet, pause the video and take a look.
VO Audio
Maya opens up the IFU and we see the single-dose pre-filled pen on the page. Zoom in to full screen. The illustration on the paper becomes the real device.
You’ll want to read through the full “Instructions for Use” carefully, before using the pre-filled pen.
Cut to Overhead shot: Maya has the two devices laid out on the kitchen island counter in front of her. She points to each as she mentions them.
The steps for injecting yourself with the DUPIXENT single-dose pre-filled pen are the same for the 200mg and 300mg dosage strengths, except for the warming time, which will be described in more detail later.
Cut to Maya in the kitchen.
To Camera Audio
In this video I'll be injecting myself with the 300mg pen. I’ll also show you how I give an injection to Emily using the 200mg pen. If you have any questions about the dosage prescribed, please contact your healthcare provider.
- Your device may appear different than what you see in this video, based on your prescribed dose.
- The DUPIXENT pre-filled pen is approved for patients 2+ years of age.
Cut to Close-up on the 300mg pen. Maya points to each part as she mentions it.
VO Audio
Let’s take a closer look at the pre-filled pen. I found it helpful to familiarize myself with the different parts of the pre-filled pen, like the cap, the window and the needle cover, before handling the pre-filled pen itself.
Contact your healthcare provider or DUPIXENT MYWAY with questions. They’re always there to help.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“I was really blown away by how much support the DUPIXENT MY WAY team provides. You feel that they’re in this with you, and they’re there to help.” (2:05 - 2:11 from DUP_CRM_Injecting DUP_12 Hi Res)
Cut to Maya in the Kitchen. Emily runs in and gives her a hug.
To Camera Audio
Maya - (Laughing) It’s time to take our DUPIXENT injection!
Emily - I’m ready!
Maya - Feel free to watch us.
Cut to Maya removing the DUPIXENT packaging from the refrigerator.
VO Audio
First, let’s take the medication out of the refrigerator. Keep the pre-filled pen and all medicines out of the reach of children. Keep unused pre-filled pens in the original carton and store in the refrigerator between 36° - 46° F (2°-8°C).
- Keep the pre-filled pen and all medicines out of the reach of children
- Keep unused pre-filled pens in the original carton and store in the refrigerator between 36° - 46° F (2°-8°C)
Maya brings the package to the kitchen island counter and opens it. She removes the IFU.
Next, let’s remove the DUPIXENT “Instructions for Use” from the packaging. You’ll want to read this completely before using the pre-filled pen. I like to keep it open and nearby when injecting for reference.
Cut to Maya in the kitchen.
To Camera Audio
Done reading? Good!
Cut to Maya removing a single pen from the packaging.
VO Audio
Now let’s take one pen out of the packaging by holding the middle of the pen body so we can check the label to ensure that the medication and dosage strengths are correct, and the expiration date has not passed.
Cut to Maya in the kitchen.
To Camera Audio
If either of those aren’t right, contact your pharmacy. Do not inject DUPIXENT if the expiration date or dosage strength are incorrect.
Cut to Maya looking at the pen.
VO Audio
Ok, now let’s take a look at the medicine through the viewing window. The liquid inside should be clear and colorless, to pale yellow. If you see an air bubble, that’s ok. An air bubble is totally normal.
A few important disclaimers about the medicine and the DUPIXENT pre-filled pen. Do not inject DUPIXENT if the liquid is discolored or cloudy, or contains visible flakes or particles. Do not use the pre-filled pen if the window is solid yellow. Do not use the pre-filled pen if it has been damaged. Do not use the pre-filled pen if the cap is missing or not securely attached.
- Do not inject DUPIXENT if the liquid is discolored or cloudy, or contains visible flakes or particles
- Do not use the pre-filled pen if the window is solid yellow
- Do not use the pre-filled pen if it has been damaged
- Do not use the pre-filled pen if the cap is missing or not securely attached
Cut to Maya in the kitchen.
To Camera Audio
If you have any questions about whether the pen is okay to use, please call DUPIXENT MYWAY, or your healthcare provider.
Cut to Maya returning the DUPIXENT packaging and unused pen to the refrigerator.
VO Audio
If you have an unused pre-filled pen, return it to the refrigerator in the original carton to protect it from light.
Cut to Maya in the kitchen.
To Camera Audio
Step One - let’s gather our materials.
Cut to Maya gathering her materials. She places the IFU on the table next to the pen, alcohol wipe, cotton ball and Sharps container.
VO Audio
We’ll keep those Instructions for Use nearby and then lay the pre-filled pen on a flat surface and let it naturally warm at a room temperature of less than 77°F (25°C). Do not store DUPIXENT pre-filled pens at room temperatures more than 77°F (25°C). Do not keep DUPIXENT at room temperature, less than or equal to 77°F (25°C) for more than 14 days. After removing a DUPIXENT pre-filled pen from the refrigerator, it must be used within 14 days or thrown away (disposed of).
- Do not store DUPIXENT pre-filled pens at room temperatures more than 77°F (25°C)
- Do not keep DUPIXENT at room temperature, less than or equal to 77°F (25°C) for more than 14 days
- After removing a DUPIXENT pre-filled pen from the refrigerator, it must be used within 14 days or thrown away (disposed of)
The recommended warming time for the 200mg pen is 30 minutes. And for the 300mg pen, it’s 45 minutes.
Cut to Maya in the kitchen.
To Camera Audio
Here’s a few more helpful tips about the DUPIXENT pre-filled pen.
Cut to the pen warming up.
VO Audio
Do not freeze or heat the pre-filled pen. Do not put the pre-filled pen into direct sunlight. Do not shake the pre-filled pen at any time.
- Do not freeze or heat the pre-filled pen
- Do not put the pre-filled pen into direct sunlight
- Do not shake the pre-filled pen at any time
Cut to Maya in the kitchen.
To Camera Audio
As the pen warms up, we can gather the additional materials needed to inject.
Cut to pen warming up. Maya brings the items into frame as she mentions them.
VO Audio
You’ll need a cotton ball, or gauze, in case there’s any bleeding. An alcohol wipe to clean the injection area, and a puncture resistant Sharps disposal container to properly dispose of the pre-filled pen after it is used.
Cut to Maya in the kitchen.
To Camera Audio
If you don’t have a Sharps disposal container, call a DUPIXENT MYWAY representative to request a complimentary one. And don’t worry. It’s ok if your Sharps disposal container looks a little different than mine.
- Your puncture resistant disposal container may look different than the one shown here
Looks like we’re just about ready to inject DUPIXENT.
Cut to Maya and Emily washing their hands in the kitchen sink.
VO Audio
So, first, let’s wash our hands thoroughly with soap and water.
Maya brings her supplies to the living room couch.
Now, take your supplies to an area where you can sit comfortably.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“I like to do my self-injection in the evening, in a quiet part of the house where I can focus.” (DUP_CRM_Injecting DUP_12 Hi Res 2:12 - 2:26)
Cut to Maya in the kitchen.
To Camera Audio
So next we need to choose an injection site. Both the stomach and thigh are acceptable except for the 5 centimeters or 2 inches around your belly button.
When I give the injection to my daughter Emily, it’s ok to inject into the outer area of the upper arm. However, that injection site is only okay because I’m giving the injection to her, not if I’m injecting myself. Oh, and don’t forget to choose a different site each time you inject DUPIXENT. That’s important!
Cut to Full Screen Title: Self Injection - Assisted Injection starts at 13:35
Cut to Maya sitting on the couch and getting ready for the injection. She opens up the IFU and lays it out on the table next to her supplies.
VO Audio
Do not inject through clothes. Do not inject into skin that is tender, damaged, has bruises or scars, or into areas with visible veins.
- [SUPER] Do not inject through clothes
- [SUPER] Do not inject into skin that is tender, damaged, has bruises or scars, or into areas with visible veins
Cut to Maya in the kitchen.
To Camera Audio
Here we go, Step 2! Prep the injection area.
Cut to Maya on the couch.
VO Audio
Clean the skin with the alcohol wipe. Wipe in a circular motion, moving from the outside to the inside. Do not touch the injection site again or blow on it before the injection. Let your skin dry before injection.
Cut to Maya in the kitchen.
To Camera Audio
Ok, are you ready for this? Next step is the actual injection. You’ve got this!
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“I prefer a self-injection just because I feel like it's more controlled when I do it.” (DUP_ADOL_Self Injection_Ana and Max_13_HI RES 1:24 - 1:30)
“My husband went with me to the doctor so that we could both be trained on the proper way to inject it and I'm just really proud that I can do it because I never thought that I would be a person that could do an injection.” (DUP_Video Booth_Self Injection_v18_HI RES 3:45 - 4:05)
Cut to Maya in the kitchen.
To Camera Audio
Step 3. The injection.
Cut to Maya on the couch. She gives herself an injection.
VO Audio
Pick up the pen by holding the middle of the pen body with the needle pointing away from you. With your other hand, pull the cap straight off.
Once you have removed the cap, do not put it back on. Do not twist the cap off.
Do not remove the cap until you are ready to inject. Do not press or touch the needle cover with your fingers. Do not try to put the cap back on once you have removed it.
- Do not twist the cap off
- Do not remove the cap until you are ready to inject
- Do not press or touch the needle cover with your fingers
- Do not try to put the cap back on once you’ve removed it
Now, place the needle cover on the skin at approximately a 90-degree angle. Make sure you can see the injection window. You’ll want to watch the window turn yellow as you give the injection
Take a deep breath.
Press down and hold the pen firmly against the skin until you can no longer see the needle cover. It disappears up into the pen itself. When you hear a “click” you know the injection has begun. It can take up to 15 seconds in total.
As you hold the pen firmly, all the way down against your skin, the injector window will start to turn yellow. Make sure you watch that window turn completely yellow.
- Be sure to watch the window turn completely yellow.
You will hear a second “click”. After the window had turned completely yellow, keep the pen pressed down on your skin as you count to five to ensure you are getting a full dose of DUPIXENT. After that, you can lift the pen straight up off the skin.
- Keep the pen pressed against your skin as you count to 5 to ensure you are getting a full dose of DUPIXENT
That’s it, the injection’s over.
You did it!
Cut to Maya in the kitchen.
To Camera Audio
If the window doesn’t turn completely yellow, or if it looks like medicine is still coming out of the pen, you may not have received a full dose. Throw away (dispose of) the pen and reach out to your healthcare provider right away. Do not give yourself a second dose without speaking to your healthcare provider.
Cut to Maya on the couch. She lightly presses a cotton ball to the injection site.
VO Audio
Lightly press a cotton ball or gauze on the injection site if you see any blood. I rarely do, but I always keep an eye out for it. If you are bleeding, you could always cover the site with a bandage. And if the bleeding doesn't stop, contact your healthcare provider.
Do not rub your skin after the injection.
- Do not rub your skin after the injection.
Here’s where that Sharps disposal container comes into play. Be sure to put the used pen and its cap into your puncture-resistant Sharps disposal container right away after use.
Do not reuse the pre-filled pen. Do not dispose of pre-filled pens in your household trash. Do not recycle your used puncture-resistant container. Keep your Sharps disposal container out of the reach of children.
- Do not reuse the pre-filled pen
- Do not dispose of pre-filled pens in your household trash
- Do not recycle your used puncture-resistant container
- Keep your Sharps disposal container out of the reach of children.
Cut to Full Screen Title: Assisted Injection
Cut to Maya in the kitchen.
To Camera Audio
Ok, that was my injection! Now let’s show you how I give my daughter Emily an injection of DUPIXENT under the skin.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“I prefer assisted injection because I get a little squeamish around needles, I don't want to look at it, I don't want to touch it. it's just not something I'm comfortable with so I'd rather have somebody else do that.” (DUP_ADOL_Self Injection_Sue and Annie_14_HI RES 1:24 - 1:35)
“I think one day I will do it myself but I think right now, assisted injection is better.” (DUP_ADOL_Self Injection_Yetunde and Ore_14_HI RES 1:45 - 1:51)
Cut to Maya in the kitchen.
To Camera Audio
I prefer the comfort of our living room couch, but Emily likes to receive her injections in the playroom. To be honest, I do too. She can play a game or read a book while I give her the injection.
Cut to Maya and Emily standing in the kitchen.
To Camera Audio
We’ve already gathered our materials, let the DUPIXENT pre-filled pen warm at room temperature and washed our hands. Let’s find a comfy spot in the playroom to inject.
Cut to Maya and Emily entering the playroom. Emily sits down and begins playing with a toy. Maya sets the pen and items needed to inject onto a small table nearby. She opens up the IFU lays it out on the table for reference.
VO Audio
I’m going to inject into Emily’s arm this time, but last time I injected into her thigh. Next time, I’ll inject into her other arm. It’s important to mix up the injection sites! Always choose a different site each time you inject DUPIXENT.
Do not inject through clothes. Do not inject into skin that is tender, damaged, has bruises or scars, or into areas with visible veins.
- Do not inject through clothes
- Do not inject into skin that is tender, damaged, has bruises or scars, or into areas with visible veins
Cut to Maya and Emily visiting with her school nurse.
VO Audio
If you’re not comfortable with giving an injection to someone, you could always ask your child’s school nurse to help out. Before I was ready, Nurse Maggie administered the injections according to the dosing regimen prescribed by Emily’s doctor for an entire school year.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“Ora's dermatologist trained us on how to do the injection under the skin, and then when we contacted DUPIXENT My Way they sent a nurse to the house to give additional training to make sure that we were comfortable giving the injection.” (DUP_ADOL_Self Injection_Yetunde and Ore_14_HI RES 1:24 - 1:44)
Cut to the playroom. Maya rubs Emily’s upper arm with the alcohol wipe.
VO Audio
Now, let’s clean the area with the alcohol wipe. Do not touch the site or blow on it before the injection. I’ll let Emily’s skin dry before I inject her.
Pick up the pen by holding the middle of the pen body with the needle pointing away from you. With your other hand, pull the cap straight off.
Once you have removed the cap, do not put it back on.
Do not twist the cap off. Do not remove the cap until you are ready to inject. Do not press or touch the needle cover with your fingers. Do not try to put the cap back on once you have removed it.
- Do not twist the cap off
- Do not remove the cap until you are ready to inject
- Do not press or touch the needle cover with your fingers
- Do not try to put the cap back on once you’ve removed it
Now, place the needle cover on the skin at approximately a 90-degree angle. Make sure you can see the injection window. You’ll want to watch the window turn yellow as you give the injection.
Pinch a fold of skin at the injection site before and during the injection. The Needle Cover should be placed on the skin at approximately a 90-degree angle.
You’ll want to pinch a fold of skin regardless of which injection site you choose – the thigh or stomach, except for the 2 inches or 5 centimeters around the belly button, or the outer area of the upper arm.
Pinching the skin is not needed for adults and children aged 12 years and older. Though, in children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. Green flag graphic appears with close up still photography image of pinch.
- Pinch a fold of skin at the injection site before and during the injection.
- Pinching the skin is not needed for adults and children aged 12 years and older.
Take a deep breath Emily. You’ve got this.
Press down and hold the pen firmly against the skin until you can no longer see the needle cover. It disappears up into the pen itself. When you hear a “click” you know the injection has begun. It can take up to 15 seconds in total.
As you hold the pen firmly, all the way down against the skin, the injector window will start to turn yellow. Make sure you watch that window turn completely yellow.
- Be sure to watch the window turn completely yellow
After you have heard a second “click” and the window has turned completely yellow, keep the pen pressed against the skin and slowly count to five. This helps to ensure you are giving a full dose of DUPIXENT. After that, you can lift the pen straight up off the skin.
- Keep the pen pressed against the skin as you count to five to ensure you are giving a full dose of DUPIXENT
That’s it, the injection’s over. You did it!
Cut to Maya in the kitchen.
To Camera Audio
Remember, if the window does not turn completely yellow, or if it looks like medicine is still coming out of the pen, you may not have received a full dose. Dispose of (throw away) the pen and contact your healthcare provider right away. Do not give a second dose without speaking to your healthcare provider.
Cut to the playroom. Maya presses a cotton ball against Emily’s injection site, then adheres a fun, kid bandaid over the spot.
VO Audio
Lightly press a cotton ball or gauze on the injection site if you see any blood. If you are bleeding you could always cover the site with a bandage. And if the bleeding doesn’t stop, contact your healthcare provider.
Do not rub your skin after the injection.
- Do not rub the skin after the injection.
Be sure to put the used pen and its cap into a puncture-resistant Sharps disposal container right away after use.
Do not reuse the pre-filled pen. Do not dispose of pre-filled pens in your household trash. Do not recycle your used puncture-resistant container. Keep your Sharps disposal container out of the reach of children.
- Do not reuse the pre-filled pen
- Do not dispose of pre-filled pens in your household trash
- Do not recycle your used puncture-resistant container
- Keep your Sharps disposal container out of the reach of children.
Follow your local guidelines and ask your healthcare provider for the appropriate way to dispose of the container once it is full.
Cut to Maya in the kitchen.
To Camera Audio
And don’t forget to keep track of your injection date and site. We’ve got a weekly planner that helps us keep track. Other’s use digital calendars or white boards. Whatever helps you remember to take your DUPIXENT injection.
Cut to DUPIXENT MyWay® Patient Ambassador Testimonials:
“I write DUPIXENT on my calendar at home and in my pocket calendar to help me remember when to take it. I've got my self injection routine down. I'm comfortable with it.” (DUP_CRM_Injecting DUP_12 Hi Res 2:27 - 2:37)
Cut to Maya in the kitchen.
To Camera Audio
Thank you for joining us today. Remember, you can re-watch this video as often as you like to refresh your memory. Contact your healthcare provider or DUPIXENT MYWAY with questions.
ISI & Indications Scroll
IMPORTANT SAFETY INFORMATION & INDICATIONS
Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.
Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:
- have eye problems.
- have a parasitic (helminth) infection.
- are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
- are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.
Tell your healthcare provider about all the medicines you take, including prescription and over-the- counter medicines, vitamins, and herbal supplements.
Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines; have asthma and use an asthma medicine; or have atopic dermatitis, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, or prurigo nodularis and also have asthma. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.
DUPIXENT can cause serious side effects, including:
- Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
- Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an exam if needed.
- Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
- Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.
The most common side effects include:
- Eczema: injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, dry eye, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).
- Asthma: injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.
- Chronic Rhinosinusitis with Nasal Polyposis: injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, high count of a certain white blood cell (eosinophilia), gastritis, joint pain (arthralgia), trouble sleeping (insomnia), and toothache.
- Eosinophilic Esophagitis: injection site reactions, upper respiratory tract infections, cold sores in your mouth or on your lips, and joint pain (arthralgia).
- Prurigo Nodularis: eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, herpes virus infections, common cold symptoms (nasopharyngitis), dizziness, muscle pain, and diarrhea.
Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver.
Please see accompanying full Prescribing Information including Patient Information.
INDICATIONS
DUPIXENT is a prescription medicine used:
- to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.
- with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 6 years of age.
- with other medicines for the maintenance treatment of chronic rhinosinusitis with nasal polyposis (CRSwNP) in adults whose disease is not controlled. It is not known if DUPIXENT is safe and effective in children with chronic rhinosinusitis with nasal polyposis under 18 years of age
- to treat adults and children 1 year of age and older with eosinophilic esophagitis (EoE), who weigh at least 33 pounds (15 kg). It is not known if DUPIXENT is safe and effective in children with eosinophilic esophagitis under 1 year of age, or who weigh less than 33 pounds (15 kg).
- to treat adults with prurigo nodularis (PN). It is not known if DUPIXENT is safe and effective in children with prurigo nodularis under 18 years of age.
US.DUP.23.10.0679
