HERE’S TO 5 YEARS SINCE INITIAL FDA APPROVAL FOR ADULT PATIENTS (18+ YEARS) WITH UNCONTROLLED MODERATE-TO-SEVERE ATOPIC DERMATITIS.a

a FDA approved since 2017 for adults, 2019 for teens (aged 12-17 years) and 2020 for children (aged 6-11 years) and 2022 for young children (aged 6 months-5 years) with uncontrolled moderate-to-severe atopic dermatitis.

DUP.22.06.0381

A BREAKTHROUGH ECZEMA TREATMENT

DUPIXENT is a biologic that works by targeting an underlying source of inflammation that could be a root cause of your uncontrolled moderate-to-severe eczema.

HELPS HEAL

DUPIXENT Helps Heal Your Skin From
Within™ for noticeably clearer skin and
less itch.

HELPS REDUCE INFLAMMATION

DUPIXENT helps control a source of
inflammation that contributes to your eczema.

NOT AN IMMUNOSUPPRESSANT

DUPIXENT is not an immunosuppressant or steroid.

THE ROLE OF INFLAMMATION IN ATOPIC DERMATITIS

Normal Skin
A healthy immune system produces little to no inflammation on the skin.

Atopic Dermatitis Skin
Immune systems of those with eczema may produce more inflammation than normal, contributing to flare‑ups on the surface of the skin.

Atopic Dermatitis Skin Treated
With DUPIXENT

DUPIXENT may help reduce this inflammation and the symptoms of eczema to help make skin noticeably clearer.

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Transcript

VO:

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information.

Individual results with DUPIXENT may vary.

KATHY:

Hi, I’m Kathy. I treat my severe atopic dermatitis with DUPIXENT. When I look back at my journey and how I got here, I can tell you that finding the right eczema specialist is very important.

At one point, I was working with a dermatologist, and I felt I had my eczema under control. But then I experienced a major flare-up, and my doctor wasn’t sure what else he could do. So, he referred me to another specialist, and I’m really glad that he did!

My new doctor turned out to be an experienced eczema specialist who’s also an assistant clinical professor at a nearby university.

She walked into the exam room, took one look at me, and said, “I know exactly how to help you.” We started working together, and eventually, my doctor felt that DUPIXENT could help me manage my symptoms. After discussing the risks and benefits, we decided to move forward with treatment.

With DUPIXENT, my skin started to clear over time, and I experienced less itching. Today, I have more control over my eczema symptoms, which is a big relief! So, if you’re not getting the results you want with your current treatment plan, look for an eczema specialist who can help you explore other options to help control your symptoms. Sometimes having the right doctor can make a big difference! And now you know a piece of my DUPIXENT journey. Thanks for watching!

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children under 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Find a Specialist Who
Treats Eczema

Use this Healthgrades™ tool to easily find nearby
specialists with experience in treating children, teens,
and adults with uncontrolled moderate-to-severe
eczema (atopic dermatitis).

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Transcript

VO:

There's nothing like volunteering at the fire department.

There's nothing like hitting the waves.

But with my moderate-to-severe eczema, it hasn't always been easy.

Since my skin was so irritated and itchy.

Even worse with all my gear on.

Now I'm staying ahead of my eczema.

There's a power inside all of us to live our passion, and DUPIXENT works on the inside to help heal your skin. It helps block a key source of inflammation inside the body that can cause eczema. So, adults can have long lasting, clearer skin and fast itch relief.

Serious allergic reactions can occur that can be severe. Tell your doctor about new or worsening eye problems such as eye pain or vision changes, including blurred vision, joint aches and pain, or a parasitic infection. Don't change or stop asthma medicines without talking with your doctor.

Healing from within is a powerful thing.

Ask your eczema specialist about how DUPIXENT can help heal your skin from within.

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

A BREAKTHROUGH ECZEMA TREATMENT

See the clinical results in adults and children 6 months of age and older by choosing the appropriate audience.

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