HEALING FROM WITHIN IS A POWERFUL THING

GET AHEAD WITH CLEARER SKIN AND LESS ITCH

DUPIXENT was studied in 3 clinical trials with more than 2,100 adults with uncontrolled moderate-to-severe eczema (atopic dermatitis).

In a 52-week clinical trial, adults taking DUPIXENT + a topical corticosteroid (TCS) (compared to those taking a TCS only) saw:

 

Long Lasting Clearer Skin ~3Xsaw clear or
almost clear skin
At 16 weeks, 39% on DUPIXENT + topical corticosteroid
(TCS) saw clear or almost clear skin vs 12% on TCS only
22% saw clear or almost clear skin at 16 and 52 weeks
vs 7%, respectively
Fast Itch Relief That Lasts ~4XHAD SIGNIFICANT ITCH
REDUCTION AT ONE YEAR
51% of adults at 52 weeks had significant itch reduction
when taking DUPIXENT + TCS vs 13% on TCS only.
59% of adults saw significantly less itch vs 20% on TCS only
at 16 weeks, and 18% saw itch reduction as fast as 2 weeks vs 8% on TCS only.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

In a different type of study (open-label extension) of adults continuing on DUPIXENT long-term through ~3 years (148 weeks), the safety results were generally consistent with those seen in the adult clinical trials.

View the possible side effects of DUPIXENT in patients with moderate-to-severe eczema (atopic dermatitis).

 

What You Should Know About the Adult Patients in These Studies:

52%
Had moderate
atopic dermatitis
48%
Had severe
atopic dermatitis
~38 years
Average age
~28 years
Average duration of the disease
~55%
Average body surface area involvement

DUPIXENT HELPS HEAL THE LOOK AND FEEL OF SKIN

In clinical trials for adults, clearer skin was seen. Use the slider to view these before and after results with 16 weeks of treatment with DUPIXENT.

Real patients shown. Additional factors (including possible use of other treatments) may have impacted results. Individual results may vary.

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to see results
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GET DOWN TO THE DETAILS

Expand the boxes below to see more detailed results from the 3 DUPIXENT clinical studies with adults.

 

The majority of adult patients saw significant skin improvement and itch reduction at 1 year of treatment with DUPIXENT when used with topical corticosteroids.

These results show the percentage of adult patients who experienced the following results at 1 year (52 weeks) while taking DUPIXENT once every other week (after an initial dose of 2 injections) while using topical corticosteroids compared to patients on topical corticosteroids only.

DUPIXENT 300 mg every 2 weeks + topical corticosteroids

On topical corticosteroids only

36% of adult patients had clear or almost clear skin when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only

65% of adult patients saw at least a 75% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 22% on topical corticosteroids only

51% of adult patients had significant itch reduction at 1 year when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only

The safety profile of DUPIXENT used with topical corticosteroids through Week 52 in adults was generally consistent with the safety profile observed at Week 16.

Results at 16 weeks when DUPIXENT was used alone* compared to adult patients not taking DUPIXENT

DUPIXENT 300 mg every 2 weeks

Not taking DUPIXENT

37% of adult patients had clear or almost clear skin compared to 9% not taking DUPIXENT

48% of adult patients showed at least a 75% improvement in their skin compared to 13% not taking DUPIXENT

33% of adult patients showed at least a 90% improvement in their skin compared to 7% not taking DUPIXENT

*Results from "DUPIXENT alone" represents the average results from 2 studies.

All patients used a daily moisturizer.


Results at 16 weeks when DUPIXENT was used every other week with topical corticosteroids compared to adult patients on topical corticosteroids only

DUPIXENT 300 mg every 2 weeks + topical corticosteroids

On topical corticosteroids only

39% of adult patients had clear or almost clear skin when DUPIXENT was used with topical corticosteroids compared to 12% on topical corticosteroids only

69% of adult patients showed at least a 75% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 23% on topical corticosteroids only

40% of adult patients showed at least a 90% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 11% on topical corticosteroids only

Adult patients experienced a significant itch reduction as defined within the clinical trials
 

DUPIXENT 300 mg every 2 weeks

Not taking DUPIXENT

38% of adult patients had significant itch reduction at 16 weeks when DUPIXENT was used alone compared to 11% not taking DUPIXENT

DUPIXENT 300 mg every 2 weeks + topical corticosteroids

On topical corticosteroids only

59% of adult patients had significant itch reduction at 16 weeks when DUPIXENT was used with topical corticosteroids compared to 20% on topical corticosteroids only

Results represent the average results of 2 studies.

I’ve been dealing with severe eczema since I was a baby. I’ve had it pretty much all my life.... With DUPIXENT, I began to see my skin clear up over time, and I was itching less.

- Jessica,
DUPIXENT patient

Individual results may vary.

MORE PATIENT STORIES
  • Photograph your skin regularly; this may help you determine if DUPIXENT is having an impact.

  • Jot down your symptoms of uncontrolled moderate-to-severe eczema that you feel each month. Can you tell if your itching has decreased?

FIND A SPECIALIST WHO
TREATS ECZEMA

Use this Healthgrades™ tool to easily find nearby
specialists with experience in treating children,
teens, and adults with uncontrolled moderate-to-severe
eczema (atopic dermatitis).

Sanofi US and Regeneron do not endorse or recommend any particular physician, and search results do not include a comprehensive list of doctors in your area.

HAVE A PRODUCTIVE CONVERSATION WITH YOUR DOCTOR

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your visit to the doctor. Fill out our personalized discussion
guide to help yourself have a productive conversation
during your next visit.

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