Results in Adults

The Results Are Clearer Skin And Less Itch

DUPIXENT was studied in 3 clinical trials with more than 2,100 adults with uncontrolled moderate-to-severe eczema (atopic dermatitis).

Results from two 16-week adult clinical trials with DUPIXENT when used alone compared to adult patients not taking DUPIXENT

4XSaw
Clearer Skin
About 4X more adults taking
DUPIXENT saw clear or almost clear
skin
(37% vs 9% not taking DUPIXENT)
75%Skin
Improvement
Nearly half of adult patients saw
75% skin improvement, and some
even saw 90% improvement.
(48% vs 13% not taking DUPIXENT)
~4XHad Significant
Itch Reduction
Nearly 4X more adults had
significant itch reduction
(38% vs 11% not taking DUPIXENT)

The most common side effects in adult patients were injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.


What You Should Know About the Adult Patients in These Studies:

52%
had moderate atopic dermatitis
48%
had severe atopic dermatitis
≈38 years
Average age
≈28 years
Average duration of the disease
≈55%
Average body surface area involvement

DUPIXENT Helps Restore the Look and Feel of Skin

In clinical trials for adults, clearer skin was seen. Use the slider to view these before and after results with 16 weeks of treatment with DUPIXENT.

Real patients shown. Additional factors (including possible use of other treatments) may have impacted results. Individual results may vary.

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to see results
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Get Down to the Details

Expand the boxes below to see more detailed results from the 3 DUPIXENT clinical studies with adults.

Results at 16 weeks when DUPIXENT was used alone* compared to adult patients not taking DUPIXENT

DUPIXENT 300 mg every 2 weeks Not taking DUPIXENT

48% of adult patients showed a 75% improvement in their skin compared to 13% not taking DUPIXENT

37% of adult patients had clear or almost clear skin compared to 9% not taking DUPIXENT

33% of adult patients showed a 90% improvement in their skin compared to 7% not taking DUPIXENT

*Results from "DUPIXENT alone" represents the average results from 2 studies

All patients used a daily moisturizer


Results at 16 weeks when DUPIXENT was used every other week with topical corticosteroids compared to adult patients taking topical corticosteroids only

DUPIXENT 300 mg every 2 weeks + topical corticosteroids On topical corticosteroids only

39% of adult patients had clear or almost clear skin when DUPIXENT was used with topical corticosteroids compared to 12% on topical corticosteroids only

69% of adult patients showed a 75% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 23% on topical corticosteroids only

40% of adult patients showed a 90% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 11% on topical corticosteroids only

Adult patients experienced a significant itch reduction as defined within the clinical trials

DUPIXENT 300 mg every 2 weeks Not taking DUPIXENT

38% of adult patients had significant itch reduction at 16 weeks when DUPIXENT was used alone compared to 11% not taking DUPIXENT

DUPIXENT + topical corticosteroids Not taking DUPIXENT (taking placebo + topical corticosteroids)

59% of adult patients had significant itch reduction at 16 weeks when DUPIXENT was used with topical corticosteroids compared to 20% on topical corticosteroids only

Results represent the average results of 2 studies

The majority of adult patients saw significant skin improvement and itch reduction at 1 year of treatment with DUPIXENT when used with topical corticosteroids.

These results show the percentage of adult patients who experienced the following results at 1 year (52 weeks) while taking DUPIXENT once every other week while using topical corticosteroids compared to patients on topical corticosteroids only.

DUPIXENT 300 mg every 2 weeks + topical corticosteroids On topical corticosteroids only

36% of adult patients had clear or almost clear skin when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only

65% of adult patients saw a 75% improvement in their skin when DUPIXENT was used with topical corticosteroids compared to 22% on topical corticosteroids only

51% of adult patients had significant itch reduction at 1 year when DUPIXENT was used with topical corticosteroids compared to 13% on topical corticosteroids only

The safety profile of DUPIXENT used with topical corticosteroids through Week 52 in adults was generally consistent with the safety profile observed at Week 16.

Quick Tips
  • Photograph your skin regularly; this may help you determine if DUPIXENT is having an impact.
  • Jot down your symptoms of uncontrolled moderate-to-severe eczema that you feel each month. Can you tell if your itching has decreased?
Find a Specialist Who
Treats Eczema

Use this Healthgrades™ tool to easily find nearby specialists with experience in treating children, teens, and adults with uncontrolled moderate-to-severe eczema (atopic dermatitis).

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