SOME RELIEF MAY BE WITHIN REACH

Check out the resources available to you from the DUPIXENT MyWay® program to learn more about DUPIXENT for patients aged 6 years and older with uncontrolled moderate-to-severe eczema (atopic dermatitis).

DO ECZEMA SYMPTOMS

HAVE AN IMPACT ON YOU?

IMAGINE IF YOUR SYMPTOMS COULD BE IMPROVED

Watch this video to learn how DUPIXENT may be able to help.

View Transcript

Please stay tuned until the end of the video for full indication and Important Safety Information.

Your healthcare provider has shown you the right way to inject DUPIXENT® (dupilumab) for your uncontrolled moderate-to-severe eczema (atopic dermatitis).

And now that you’ve started taking DUPIXENT at home,

…you may find things can still come up that make it hard to stay on schedule, like…

…your never-ending to-do list at home

…or your busy schedule at work —

…maybe even unexpected travel plans or an unpredictable daily commute.

Whatever your challenges may be, it’s important to think ahead about what might get in your way

…and create a plan to make DUPIXENT a part of your routine, helping you stay on track with your treatment.

Set aside time specifically for DUPIXENT. Mark your calendar and consider setting an alarm as a reminder.

Use an existing routine to make it easier to remember DUPIXENT.

When you enrolled in DUPIXENT MyWay, you may have requested support from our Nurse Educators who can also help you keep up with your prescription refills and delivery schedule. If you would like to request Nurse Educator support, call DUPIXENT MyWay.

If you have any questions or concerns about adding DUPIXENT into your routine, be sure to talk to your healthcare provider.

Life can get challenging.

…but it’s important to remember to plan ahead while taking DUPIXENT.

And get help staying ahead of your schedule with the support from DUPIXENT MyWay.

INDICATION

DUPIXENT is a prescription medicine used to treat people aged 6 years and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.

IMPORTANT SAFETY INFORMATION

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems
  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
    • There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult. In children younger than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

DUP.21.08.0087     September 2021

SEE MORE

You may have thought living with moderate-to-severe eczema symptoms that keep coming back, despite using topical prescription treatments, is to be expected. But there's hope of getting ahead of your symptoms.

HOW DOES DUPIXENT WORK?

DUPIXENT works from the inside, targeting a source of underlying inflammation.

SEE MORE

DUPIXENT helps to heal the skin from within by specifically targeting some of the signals that contribute to persistent, underlying inflammation. By reducing inflammation in the body, DUPIXENT may help reduce some symptoms and provide noticeably clearer skin.

THE ROLE OF INFLAMMATION IN ATOPIC DERMATITIS

Normal Skin Normal Skin
Atopic Dermatitis Skin Atopic Dermatitis Skin
Atopic Dermatitis Skin Treated With DUPIXENT Atopic Dermatitis Skin Treated With DUPIXENT

DUPIXENT CLINICAL
TRIAL RESULTS

SEE MORE

DUPIXENT helps heal the skin from within.

RESULTS IN ADULTS

DUPIXENT was studied in 3 clinical trials with more than 2,100 adults with uncontrolled moderate-to-severe eczema (atopic dermatitis).
Results from two, 16-week adult clinical trials with DUPIXENT when used alone compared to adult patients not taking DUPIXENT:

Almost 4 times more patients (37%) saw clear or almost clear skin as compared with those not taking DUPIXENT (9%)

Patients experienced significant itch reduction (38% vs 11% not taking DUPIXENT), some as early as 2 weeks (10% vs 2% not taking DUPIXENT)

RESULTS IN TEENS (AGES 12-17)

In a 16-week clinical trial with 251 patients ages 12-17 with moderate-to-severe eczema, those taking DUPIXENT

Had at least a 75% skin improvement (42% vs 8% in those not taking it)

Saw clear or almost clear skin (24% vs 2% in those not taking it)

Experienced significant itch reduction (37% vs 5% in those not taking it)

RESULTS IN CHILDREN (AGES 6-11 YEARS)

In a 16-week clinical trial with 367 patients ages 6-11 years with severe eczema, of those taking DUPIXENT and a topical corticosteroid (TCS)

>2 times as many patients saw clear or almost clear skin (30% taking 300 mg every 4 weeks vs 13% on TCS only and 39% taking 200 mg every 2 weeks vs 10% on TCS only)

~4.5 times as many patients saw less itch (54% taking 300 mg every 4 weeks vs 12% on TCS only and 61% taking 200 mg every 2 weeks vs 13% on TCS only)

Your healthcare provider will tell you how much DUPIXENT to inject and how often you inject it.

After an initial loading dose of 2 injections, children 33-66 lbs took 300 mg every 4 weeks and children 67-132 lbs took 200 mg every 2 weeks.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips.

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Not an actual patient

DO YOU DEAL WITH RASHES AND INTENSE ITCHING

DESPITE USING TOPICAL PRESCRIPTION MEDICATIONS?

UNDERSTANDING ECZEMA

SEE MORE

Your Alarm Keeps Going Off

Imagine that you have a home alarm system, but it’s broken. Every single time someone even walks by your home, the alarm system goes off and sends an alert to the police. This is clearly not the appropriate response. Your alarm system needs to be fine-tuned so that it should alert you only when there's actual danger.

For many people with eczema, their immune system—like a house alarm on the fritz—may be malfunctioning. It responds to triggers inside and outside the body and leads to an itchy rash.

“I Feel Like I’ve Exhausted All of My Treatment Options.”

SEE MORE

You and your doctor worked so hard at trying to find a treatment that works for you; however, you may still feel frustrated by your symptoms. The best thing that you can do is to be open with your healthcare provider. Discuss your symptoms, treatment goals, and anything that you feel is getting in the way of your success. This kind of detail will help your healthcare provider determine what’s effective and what isn’t, as well as how best to work together.

Using The Confidence to Take Charge discussion guide, work together to figure out a plan that is both effective and manageable.

WHAT’S STOPPING YOU FROM ASKING ABOUT DUPIXENT?

Take the next step: Ask your healthcare provider about DUPIXENT today.

FIND A DOCTOR

Need a specialist who can help manage moderate-to-severe eczema?

Use this tool to find one near you.

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IMAGINE THE POSSIBILITIES WITH DUPIXENT

“I Feel OK Today.”

SEE MORE

Tell your healthcare provider about how you've been affected during the past 30 days and if you've had any uncontrolled symptoms. Use The Confidence to Take Charge discussion guide to help keep your discussion on track.

WHAT’S HAPPENING
INSIDE


When a person has eczema, their immune system reacts differently than it does in other people.

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They have an overactive immune system that is incredibly sensitive to internal and external triggers, such as stress, soap, certain fabrics, or scents. Sometimes skin reacts even when the person stays clear of common triggers.

This overreaction of the immune system may lead to inflammation and result in the familiar symptoms of redness, irritation, and itching.

MAKE A PLAN TO STAY AHEAD OF YOUR SYMPTOMS

MAKE A PLAN TO STAY AHEAD OF YOUR SYMPTOMS

SEE MORE

Use the Know What’s Happening Inside guide to help you reflect on where you’ve been on your eczema journey and set goals for where you want to go. Share it with your healthcare provider so that, together, you can make a plan—one that could include DUPIXENT.

OVERCOME SOME POSSIBLE CONCERNS ABOUT YOUR TREATMENT PLAN

Your healthcare provider is your best source of information regarding eczema and DUPIXENT. DUPIXENT MyWay is designed to provide additional support resources.

SEE MORE

Through DUPIXENT MyWay, you can

  • Learn how to have productive conversations with your healthcare provider about whether DUPIXENT is right for you
  • Get supplemental training on how to inject DUPIXENT once your healthcare provider has told you to self-inject or administer the injection for your child and has shown you the right way to do it
  • Get connected with available resources in the form of the DUPIXENT MyWay program
  • See if you’re eligible for the DUPIXENT MyWay Copay Card*

*THIS IS NOT INSURANCE. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any state pharmaceutical assistance programs. Program has an annual maximum of $13,000. Additional terms and conditions apply.

FINDING DUPIXENT:

AN INTERVIEW WITH RHONDA

Hear an actual patient discuss how she found DUPIXENT.

In about 30 seconds, you're going to hear a real patient story that will discuss life with uncontrolled moderate-to-severe eczema (atopic dermatitis), as well as potential treatment with DUPIXENT® (dupilumab). DUPIXENT is a prescription medicine used to treat adults and children 6 years of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age. Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT. Please listen to the Full Important Safety Information and Indication at the end of this audio.

Interviewer: We are talking with Rhonda today. She is going to share what led her to DUPIXENT.

Rhonda, you’ve had moderate-to-severe eczema your whole life. What challenges have you faced?

Rhonda: Well, as I look back on the effects my type of eczema has had on me, I realize that I didn’t know how ill I was. I didn’t know it was a real disease that was affecting me so much. It was all I ever knew.

Interviewer: It seemed like the symptoms from eczema were just part of life for you because you’d never lived without them. Tell me more about what it was like growing up.

Rhonda: I started showing signs when I was 6 months old. It was not easy on my family—the constant crying, waking them up all the time. Once I was in school, I was self-conscious about how my eczema affected others.

Interviewer: Affected others?! But how did it affect you? Can you share some examples with us?

Rhonda: Well, for example, in 4th grade I left the janitor a note thanking him for cleaning up the dead skin around my desk. And I remember one doctor recommended putting medical tape over and around my fingertips so I wouldn’t be able to scratch.

Interviewer: And what happened as you grew up?

Rhonda: As I got older, I tried every treatment every doctor prescribed. But nothing seemed to adequately soothe my skin or clear the red, scaly patches. When I wore pantyhose to hide my legs, it caused even more problems for my skin. When I took them off, little pieces of skin would pop out on the floor.

By then, I felt like I’d tried everything without much change.

Interviewer: It sounds like you really believed your eczema would always be uncontrolled, huh?

Rhonda: Oh, yeah, by the time I was in my late 50s, I’d given up on trying to find a treatment that worked for me.

Interviewer: So how did you find DUPIXENT and get the help you needed?

Rhonda: Well, my dermatologist—we had such a good relationship. I trusted her. She’d just heard about a clinical trial for DUPIXENT and thought of me. I jumped at the chance.

Interviewer: I bet you did! So, were you nervous when you first started your injections?

Rhonda: I was a little nervous about self-injections. I wasn’t sure if I would be able to stick a needle into my own body. But, like most things we dread, the buildup was worse than the act.

Interviewer: Did you use any of the resources from DUPIXENT MyWay® for support, like the supplemental injection video?

Rhonda: I did use DUPIXENT MyWay. It’s a very good source of information and support.

Interviewer: And how are you doing now that you're on DUPIXENT?

Rhonda: I’ve seen my skin become more clear. I have significantly less itching, redness, and inflammation than I once did. My skin feels smoother to me, which is not something I’ve really ever experienced before.

Interviewer: I’m glad to hear that, because DUPIXENT was compared to placebo in two, 16-week clinical studies in adults. Almost 4 times more patients taking DUPIXENT saw clear or almost clear skin compared to those not taking DUPIXENT (37% vs 9%). Adult patients taking DUPIXENT experienced significant itch reduction (38% vs 11%). The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips. Is there anything else you’d like to share with us?

Rhonda: I hope I’ve helped even one person to realize how important it is to be proactive and to work with their eczema specialist to find that right treatment for them.

Interviewer: Rhonda, thank you so much for talking with us today.

Please listen to the following Important Safety Information.

IMPORTANT SAFETY INFORMATION

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems
  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
    • A pregnancy registry for women who take DUPIXENT during pregnancy collects information about the health of you and your baby. To enroll or get more information call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children under 12 years of age, DUPIXENT should be given by a caregiver.

INDICATION

DUPIXENT is a prescription medicine used to treat people adults and children 6 years of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.

DUP.21.10.0324     January 2022

“My Healthcare Provider Tells Me That My Skin Looks Good.”

SEE MORE

Your skin may look and even feel good today, but if your eczema is not adequately controlled, it’s important to let your healthcare provider know that there are many other days when you are negatively affected by it.

You can take charge of the conversation by going in prepared, knowing what you want to talk about, and letting your healthcare provider know how your eczema is affecting you. Use The Confidence to Take Charge discussion guide to plan ahead.

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AN OPEN DISCUSSION CAN HELP LEAD TO AN APPROPRIATE PLAN

Listen to how a doctor and patient work together to discuss DUPIXENT as a possible treatment option.

Announcer: In about 30 seconds, you're going to hear how an adult patient and doctor might discuss life with uncontrolled moderate-to-severe eczema (atopic dermatitis) and discuss potential treatment with DUPIXENT® (dupilumab). DUPIXENT is a prescription medicine used to treat people aged 6 years and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age. Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Please listen to the Important Safety Information at the end of this audio.

Doctor: Hi, Jordan. It’s good to see you again. What brings you in today?

Patient: Well…I am using my topical creams and they're OK. I guess I do still have itching, though, even when I use them.

Doctor: Can you tell me more?

Patient: Sure. My skin has been really dry and red lately. I don’t like all the itching and redness.

Doctor: Hmm, maybe it’s time to try something else for your symptoms. Have you heard of DUPIXENT? It’s a medication used to treat adults like you with uncontrolled moderate-to-severe eczema with symptoms, such as itching.

Patient: Yeah, I have heard of it. So, is it another steroid?

Doctor: DUPIXENT is not a steroid. It helps treat a source of inflammation under your skin to address the symptoms you see. DUPIXENT works to get ahead of eczema symptoms and helps to heal the skin from within. Some of my adult patients started feeling relief as early as 2 weeks after they started.

Patient: Oh, OK. Can you tell me more about it?

Doctor: You have to inject it, and it’s for both moderate and severe patients whose disease is uncontrolled. If we choose to move forward with DUPIXENT as a treatment option, I can teach you how to properly self-inject at the time of your first scheduled injection.

Patient: All right. But what side effects might I have?

Doctor: The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.

Patient: OK… How will I know if it’s working?

Doctor: DUPIXENT was compared to placebo in two, 16-week clinical studies in adults. Nearly half of patients saw 75% skin improvement, and some even saw 90% skin improvement, at 16 weeks. Almost 4 times more patients taking DUPIXENT saw clear or almost clear skin compared to those not taking DUPIXENT (37% vs 9%). Adult patients experienced significant itch reduction (38% taking DUPIXENT vs 11% not taking DUPIXENT), some as early as 2 weeks (10% taking DUPIXENT vs 2% not taking DUPIXENT).

Patient: Wow, it’s great to hear that DUPIXENT has helped others.

Doctor: So, it sounds like you’re considering DUPIXENT?

Patient: Yes, I am. I’m excited to try another option for my symptoms.

Doctor: I’m glad you shared your experience with me, Jordan. Now I better understand how I can help you, so let’s talk about how to get started.

Please listen to the following Important Safety Information.

IMPORTANT SAFETY INFORMATION

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems
  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
    • There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult. In children younger than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

DUP.20.02.0297     June 2020

“I’m Having a Hard Time Remembering the Severity or Timing of Symptoms.”

SEE MORE

Track your symptoms by keeping a notebook or using your phone as a journal. Take pictures and jot down notes so you can reference this information when you need it. That way, you have the information you need during these discussions with your healthcare provider.

Remember to track the severity of your itch or redness—whether anything is different when the temperature or seasons change, and any identified triggers. Use The Confidence to Take Charge discussion guide, and share this information with your healthcare provider to work together to find a solution that is best for you.

“I Don’t Know How to Start a Conversation About DUPIXENT.”

SEE MORE

Your healthcare provider may consider several treatments when trying to find what works best for you if you have uncontrolled moderate-to-severe eczema. DUPIXENT may be one of those treatment options if you have already tried prescription topicals.

If you are interested in finding out whether DUPIXENT is the right treatment for you, you can use this helpful conversation guide. The guide provides some conversation starters, so you can work with your healthcare provider to better understand treatment options and find a plan you both can be comfortable with.

LOOK TO OUR NURSES FOR ADDITIONAL SUPPORT

View Transcript

SHARI, Nurse Educator

I grew up in a very small town—one stop light, if you blink you might miss it. Very quaint. The small-town environment lends to the type of work that I do, more one-on-one with our patients.

My name is Shari and I’m a registered nurse with DUPIXENT MyWay®.

I chose to be a nurse because I wanted to help people, and I believe that people should be in service to others.

Being a nurse for DUPIXENT MyWay is very rewarding. I really enjoy the patient interaction. I’m ready to make a difference. I’m ready to help our patients to have the confidence to proceed with their journey.

Our nurses work remotely from our homes. So, we step into our offices, we’re going into a nice relaxing environment.

When our patients call in, they get to speak to a real person, a experienced clinician who can provide them support along their journey.

We provide general product support and education, as well as supplemental injection training, and injection and refill reminder calls.

Every day is different depending on the type of calls that we have. Some of the common questions we get: “How much is it going to cost me?” “When will I get started?” “How do I take my DUPIXENT injections when I’m traveling?”

We have multiple resources available for patients. We have the ability to send out package inserts that include all the important safety information for DUPIXENT. For patients wanting a copay card, they can access that by visiting our product website at DUPIXENT.com.

One of my favorite parts of providing nursing care to our patients is being able to walk them through their journey, hold their hand through the process, just to give them confidence along the way and we always want them to know that they have our support.

LAURIE, Field Nurse

I’m Laurie. I’m a registered nurse with DUPIXENT MyWay. I’ve been with DUPIXENT MyWay since the very beginning.

I give supplemental injection training to the patient and the patient’s caregiver.

When I was very young, I knew that I wanted to be a nurse. I wanted to go out and make a difference and help people.

When I get the order for the patient, I get really excited. I travel to see the patients—sometimes for hours. I make sure that I gather all of the things that I may need to help the experienced person, and then the person that’s never even touched a needle.

I think it’s very important for me as a nurse to go and teach these patients. Not only to teach them how to give themselves the medicine, but also to just come and give them encouragement, and show them kindness and patience.

When I go to see the patient, I can’t wait to travel, no matter how far it is. I have a training kit that has a training syringe in it. And that helps us so that we can practice before we do the real thing.

I can’t wait to go and meet them, and see where they are in their life, and be excited for them.

I help them to relax. Sometimes they can just take a deep breath, we’ll go slow, think about their favorite place, think about something that reminds them and makes them happy and calms them down.

I went to this patient’s house and he seemed very standoffish. You could tell that the patient was just not comfortable. He was anxious, he wouldn’t give me eye contact. So, I asked the parents, “would it be OK if I just come back the next day?”

I think it’s very important to just be patient. Make it into their routine and let them go at their own pace. We have time. They have set aside this time for us to learn. And for me to teach.

Sometimes at the end of the training, I’ll get some questions about, “You know, we did great today, but what else? What if when you leave, I don’t know what to do and it’s time for me to give myself my injection again?” I can refer the patient to the DUPIXENT website for more resources and there’s also a Nurse Educator phone number.

I like to go out and do this job. It’s just really neat. It’s neat to go in and get to know people.

DUP.20.11.0038

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DUPIXENT MyWay provides support from nurses, either virtually or via phone. Take a minute to watch these nurses explain how they may help throughout the treatment journey with DUPIXENT.

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HEAR FROM ACTUAL PATIENTS:

JENNIFER’S STORY

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I knew at age 5 that I wanted to be a nurse. Around this time, I was also diagnosed with eczema. By the time I was a teenager, my skin was getting worse. The prescription topical and oral steroids I was prescribed helped me, however, I was still not well controlled…which marked the beginning of my search for treatment options that might work better for me.

An old high school friend reached out via social media. She was practicing as an eczema specialist in our area. [She] mentioned a medication that she thought I should try called DUPIXENT. I admit, I was skeptical. Honestly, is there anyone with eczema who hasn’t gotten unsolicited advice about how to help “fix” your skin? After thinking it over for a few months and speaking with my healthcare provider, I finally agreed to try DUPIXENT.

Within weeks, my skin was becoming clearer. I only had one small patch of dry skin on my wrist. As a nurse, I’m an advocate for my patients. It’s what I do. As someone with moderate-to-severe atopic dermatitis, I’m my own advocate.

This is my personal story. Individual results vary. Serious side effects of DUPIXENT include the risk of allergic reactions that can sometimes be severe, eye problems, and joint aches and pain. The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips. Please see additional Important Safety Information below.

If I could impart words of inspiration to others suffering from this condition, it would be that moderate-to-severe atopic dermatitis is not who you are, but what you may be able to overcome.

Get support throughout your treatment with DUPIXENT.

As a member of DUPIXENT MyWay, you get

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ARE YOU READY?

There may be a way to help manage uncontrolled moderate-to-severe eczema.

Ask your doctor about DUPIXENT.

“I’m still having symptoms, even with prescription topical treatment.”

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DUPIXENT is a prescription medicine used to treat adults and children 6 years of age and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.

RESULTS IN ADULTS

DUPIXENT was studied in 3 clinical trials with more than 2,100 adults with uncontrolled moderate-to-severe eczema (atopic dermatitis).
Results from two, 16-week adult clinical trials with DUPIXENT when used alone compared to adult patients not taking DUPIXENT:

Almost 4 times more patients (37%) saw clear or almost clear skin as compared with those not taking DUPIXENT (9%)

Patients experienced significant itch reduction (38% vs 11% not taking DUPIXENT), some as early as 2 weeks (10% vs 2% not taking DUPIXENT)

RESULTS IN TEENS (AGES 12-17)

In a 16-week clinical trial with 251 patients ages 12-17 with moderate-to-severe eczema, those taking DUPIXENT

Had at least a 75% skin improvement (42% vs 8% in those not taking it)

Saw clear or almost clear skin (24% vs 2% in those not taking it)

Experienced significant itch reduction (37% vs 5% in those not taking it)

RESULTS IN CHILDREN (AGES 6-11 YEARS)

In a 16-week clinical trial with 367 patients ages 6-11 years with severe eczema, of those taking DUPIXENT and a topical corticosteroid (TCS)

>2 times as many patients saw clear or almost clear skin (30% taking 300 mg every 4 weeks vs 13% on TCS only and 39% taking 200 mg every 2 weeks vs 10% on TCS only)

~4.5 times as many patients saw less itch (54% taking 300 mg every 4 weeks vs 12% on TCS only and 61% taking 200 mg every 2 weeks vs 13% on TCS only)

Your healthcare provider will tell you how much DUPIXENT to inject and how often you inject it.

After an initial loading dose of 2 injections, children 33-66 lbs took 300 mg every 4 weeks and children 67-132 lbs took 200 mg every 2 weeks.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.

If you or a loved one are experiencing uncontrolled symptoms due to moderate-to-severe eczema while using topical prescription medicines, consider whether DUPIXENT may be able to help.

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HEAR FROM ACTUAL PATIENTS:

DEBBIE’S STORY

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Over the course of several years, I tried all kinds of different things, including topical prescription therapies, to manage my eczema. The patches never went away; they would just move to different parts of my body. It was becoming harder to stay motivated when I didn’t see any relief. I felt as if I were the only person who had this disease.

My husband attended another [National Eczema Association] conference with me. Afterward, he told me that he’d never realized eczema was such a big deal. When he said that, it was a total “aha” moment for me. At that moment, I realized that it was OK for me to express my heartache about this disease. This disease is a big deal.

Taking the leap

Through a friend, I learned about DUPIXENT. It was a leap of faith. After discussing with my healthcare provider, it turned out to be a good decision. My husband was the first person to notice how clear my skin was becoming. Then, I realized that the constant itchy feeling under my skin had calmed down. I noticed that my skin wasn’t as dry.

This is my personal story. Individual results vary. Serious side effects of DUPIXENT include the risk of allergic reactions that can sometimes be severe, eye problems, and joint aches and pain. The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips. Please see additional Important Safety Information below.

I realize now that I had to go through the ups and downs to get where I am today. Each phase of my journey was an integral part of my story.

ASK YOUR DOCTOR IF DUPIXENT MAY BE RIGHT FOR YOU.

WONDERING WHAT TO SHARE WITH YOUR DOCTOR?

Get some guidance to help with common barriers that may come up in your discussion about DUPIXENT.

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Use The Confidence to Take Charge guide to help you prepare for a discussion about your moderate-to-severe eczema with your healthcare provider.

TALK TO A DOCTOR VIRTUALLY

Get tips for your telehealth visit, including navigating technology, organizing your thoughts, and discussing your condition and DUPIXENT in a virtual setting.

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Learn how to make the most of a phone or video-chat appointment with your healthcare provider.

Download the guide now.

“I’m Worried About the Cost of Treatment.”

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Cost is a common concern for some people considering prescription treatment. That’s where DUPIXENT MyWay may help. The program provides guidance on how to navigate through the insurance process. DUPIXENT MyWay offers various ways that may help reduce the out-of-pocket cost of DUPIXENT. For example, with the DUPIXENT Copay Card, eligible, commercially insured patients may pay as little as a $0* copay per fill of DUPIXENT.

If you’re looking for live support to help understand these options or answer any questions you might have about DUPIXENT, our dedicated Nurse Educators are available at 1-844-DUPIXENT (1-844-387-4936), option 1 to assist you.

*THIS IS NOT INSURANCE. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any state pharmaceutical assistance programs. Program has an annual maximum of $13,000. Additional terms and conditions apply.

EXPLORING FINANCIAL ASSISTANCE OPTIONS?

LEARN ABOUT THE DUPIXENT MyWay COPAY CARD

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With the DUPIXENT MyWay Copay Card, eligible, commercially-insured

patients may pay as little as a $0* copay per fill of DUPIXENT, maximum of $13,000 per patient per calendar year. And, if you're eligible, you can sign up and receive your card today.

You may be eligible for the copay card if you

  • Have commercial insurance, including health insurance exchanges, federal employee plans, or state employee plans
  • Are a resident of the 50 United States, the District of Columbia, Puerto Rico, Guam, or the USVI
  • Are prescribed DUPIXENT for an indication approved by the US Food and Drug Administration

Call 1-844-DUPIXENT (1-844-387-4936), option 1 or visit DUPIXENT.com to apply for a copay card. Read more here.

*THIS IS NOT INSURANCE. Not valid for prescriptions paid, in whole or in part, by Medicaid, Medicare, VA, DOD, TRICARE, or other federal or state programs including any state pharmaceutical assistance programs. Program has an annual maximum of $13,000. Additional terms and conditions apply.

“I’m Nervous About Injections.”

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The idea of an injection may be intimidating. However, with the help of your healthcare provider, and the supplemental support available from DUPIXENT MyWay, you may become more comfortable with injections.

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STILL FEELING UNCERTAIN?

If you find yourself feeling uneasy about injections at any point, it’s always best to first consult your healthcare provider. Watch this video—it may help you manage feelings of uncertainty and help you stay on track with DUPIXENT.

View Transcript

Need help keeping thoughts from getting in your way? You can change your perspective to help stay the course.

When you’re thinking about doing something you consider difficult…or that is just…out of your comfort zone, it’s not uncommon to feel nervous or uneasy.

But…what happens when those feelings lead to thoughts like, “I’ll never be able to do this” or “It’s just too hard?”

Thoughts like these can be overwhelming, and may not be helpful.

In fact, unhelpful thoughts can negatively affect what you’re trying to accomplish…they may even keep you from trying it at all.

So, how can you help keep these thoughts from getting in your way?

Remember that thoughts are not always facts.

If you change how you look at them, you may be able to take their power away.

See if you can do that by changing your perspective and looking at this situation a little differently.

Try to focus on what you are trying to do and why.

What’s the reason for doing it?

Think about another difficult situation you’ve overcome.

How did that situation affect you?

Recognize that you don’t have to take on challenges alone.

Who or what can support you in this situation?

Take time to get familiar with the task at hand.

What resources can you use to help guide you?

Taking this different view might just be what’s needed

to help you stay the course and give this thing a try!

Of course, even after you decide to do it, nervous feelings and unhelpful thoughts might still come up…but that’s OK!

Just remind yourself:

Thoughts are not always facts.

And if you can change how you view them, you may be able to change how you feel and help keep yourself on track.

Before long—and with proper training and practice—you can start feeling more confident to tackle the challenge, time and again.

You may even notice that what you saw before as unfamiliar and intimidating might not be as difficult to navigate as you thought.

So…let’s do this!

See if you can change your thoughts to help build your confidence and work toward your goal.

Whenever you are facing a situation that’s making you feel nervous, remember:

You have the power to change your thoughts and look at things from a more encouraging perspective.

  • Remember to keep your reason for doing this in mind to help guide you along the way.
  • Tell yourself that you’ve tackled challenges before. You can do it again.
  • Rely on resources to help you through difficult situations. Feeling supported can build confidence.
  • Focus on what you want to accomplish and what you hope to gain.

Watch this video whenever you need a reminder of how you already have and can continue to tackle new challenges.

Have questions? Call a DUPIXENT MyWay® Nurse Educator at 1-844-DUPIXENT (1-844-387-4936), option 1.

DUP.20.09.0057

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NAVIGATE THROUGH YOUR INJECTION CONCERNS

  • Focus on what you’re hoping to accomplish with eczema treatment
  • Remember to keep your reason for doing this in mind to help guide you along the way
  • Think of challenges you’ve overcome before
  • Reach out to your personal support system

Refer to the DUPIXENT MyWay support resources designed to help you feel more comfortable with the injection process, like the supplemental injection training videos (after you have been trained by your healthcare provider)

Contact DUPIXENT MyWay Nurse Educators at 1-844-DUPIXENT (1-844-387-4936), option 1

GETTING STARTED WITH INJECTIONS

With DUPIXENT MyWay, you can get supplemental injection training and hear about other patient experiences to help you feel more prepared to use DUPIXENT.

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HEAR FROM ACTUAL PATIENTS: RHONDA’S STORY

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As a little girl, the most vivid memory I have is of constant itching. The itching and scratching was a cycle that never seemed to end. Nothing seemed to soothe my skin or clear the red, scaly patches. Sometimes, I itched so badly I didn’t want anything to touch my skin, not even the sheets.

I tried many things, including topical prescription therapies, but had given up on trying to find a treatment that worked for me. I decided, almost on a whim, to stop by and say hello to one of my previous dermatologists. When she saw me, she started telling me about this [treatment] for people with uncontrolled moderate-to-severe atopic dermatitis. She said, “As soon as I heard about it, I thought of you.”

Since starting on DUPIXENT, I have seen my skin clear. I have significantly less itching, redness, and inflammation than I once did. My skin feels smoother to me, which is not something I really ever said before. I feel so lucky that I decided to swing by and say hi to my former dermatologist. I might not have known anything about DUPIXENT had I not gone to see her.

This is my personal story. Individual results vary. Serious side effects of DUPIXENT include the risk of allergic reactions that can sometimes be severe, eye problems, and joint aches and pain. The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, and cold sores in your mouth or on your lips. Please see additional Important Safety Information below.

HOW TO ADMINISTER DUPIXENT

For supplemental injection support, watch these videos or contact a DUPIXENT MyWay Nurse Educator.

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Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. Your healthcare provider will also provide additional guidance, such as the need to choose a different injection site each time. For supplemental injection training, watch the videos and read the 200-mg Pre-Filled Syringe Instructions for Use, the 300-mg Pre-Filled Syringe Instructions for Use, the 200-mg Pre-Filled Pen Instructions for Use, or the 300-mg Pre-Filled Pen Instructions for Use. The 200-mg pre-filled pen and the 300-mg pre-filled pen are approved for patients 12 years of age and older. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children under 12 years of age, DUPIXENT should be given by a caregiver.

PRE-FILLED SYRINGE SELF-INJECTION

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HEAR FROM AN EXPERT ON COPING WITH CAREGIVER CONCERNS

You have the best interests of your child (aged 6-11 years) or teen (aged 12-17 years) in mind, but it can still be hard to make decisions that affect them. Along with working with your healthcare provider, learning how to cope with common challenges caregivers face when making those decisions may help you make the best choice for your family.

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The Common Thread:

Asking an Expert

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If your child’s current medicines aren’t working as well as you’d hoped, it can be difficult to know what steps to take. You may also have some questions about treating their eczema.

Can you address their symptoms with a proactive approach?
Consider that DUPIXENT targets and proactively treats an underlying cause of your child’s eczema and may mean less bothersome symptoms.

How will you make an injection a part of your family routine?
The idea of trying something new can seem overwhelming, and it’s normal to worry about how you’ll make it work for your family. Learning more about administering DUPIXENT may help ease your concerns. And with the pre-filled pen (200-mg dose or 300-mg dose, ages 12+ years), your child may have the option to treat their eczema without ever seeing the needle.

TEEN (AGED 12-17)

 

PICTURE THE POSSIBILITIES

WITH ANOTHER TREATMENT OPTION

Help motivate your teen to consider treatment by thinking about what may be possible with DUPIXENT.

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Start the conversation with your teen about seeing if DUPIXENT is right for them. It can be as simple as motivating them to think about trying something new.

You can start with these images—pick one that you think your teen will like. Then save it to your phone and send it to them by text. By sending the picture, you’re opening the door to a conversation about the possibilities with a different treatment option.

THE OPEN-ENDED STARTER

It’s up to you to fill in the details about your teen’s eczema.

DREAM BIG

Ask your teen what they think might be possible with treatment.

DREAM BIG

Ask your teen what they think might be possible with treatment.

TEEN (AGED 12-17)

TOGETHER WITH YOUR TEEN, PREPARE TO TALK WITH THEIR DOCTOR

Complete this discussion guide to help get the most out of your teen’s next appointment.