What is Atopic Dermatitis?

Debbie,
Real patient. Individual
results may vary.

Atopic Dermatitis—The Most Common Form of Eczema

You or your loved one’s eczema could be atopic dermatitis and might be uncontrolled despite treatment with topical prescription treatments.

Know what to look for

A cause of eczema is inflammation beneath your skin, and your current topical prescription medications may not be enough to control your moderate-to-severe eczema. If your current topical prescription medications are not enough, you may want to explore another option.
Talk to an eczema specialist if you or your loved one:

1

Hide skin from others

2

Have eczema that keeps
coming back

3

Take oral steroids more than once a year

4

Take immunosuppressants more than once a year

Just the Facts

  • You or your loved one’s eczema could be more than a skin condition. It could be atopic dermatitis, the most common form of eczema, and might be uncontrolled despite the use of topical prescription treatments.
  • Atopic dermatitis is an immunological disease where the immune system causes more inflammation than normal.
  • The overactive immune system under the surface may lead to increased inflammation on the surface and is a contributing factor to the itchy patches on the skin.
  • Atopic dermatitis commonly appears on the face, hands, knees, neck, elbows, and ankles.
  • Experiencing frequent flare-ups while using topical prescription therapies may mean that moderate-to-severe atopic dermatitis is not well controlled.
Hear from a patient who wondered if her eczema was severe enough for DUPIXENT.

Transcript:

VO:

DUPIXENT® (dupilumab) is a prescription medicine used to treat people aged 6 years and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information.

Before starting DUPIXENT, you should talk to your doctor about all the medical conditions you have and medications you are taking.

You and your doctor should also discuss the potential benefits and risks of treatment with DUPIXENT including the most common side effects such as injection site reactions and some serious side effects such as allergic reactions, including anaphylaxis, and eye problems.

There is no cure for atopic dermatitis. DUPIXENT can help reduce the signs and symptoms of eczema. Patients’ individual results with DUPIXENT may vary.

Rachel:

Hi, I'm Rachel, and I want to share with you one big misconception I had about my severe atopic dermatitis. And that is… I never really thought about how serious it could be. In my mind, it was just this annoying condition that I had to deal with and could get by with some prescription creams and ointments. So, when my doctor recommended DUPIXENT, I was a little surprised.

The idea of injecting myself was new to me. I mean, I’d heard of self-injections for other diseases like diabetes, but not for eczema. And, to me, having an injection for something happening on my skin was more than I expected.

I remember thinking, “Is this really the point I’ve reached in treating my eczema?” But then again, I tried different prescription creams and ointments. I even made dietary changes like cutting out dairy and meat. I wasn’t getting the results I was looking for, and hoping that it would just go away was wishful thinking. I realized my eczema was serious, and I needed to make a change. That’s when my doctor and I took the next step and moved forward with DUPIXENT. And now, I see my self-injection with DUPIXENT every 2 weeks as a part of my life.

So, that’s a little bit of my DUPIXENT journey. Thanks for watching!

VO:

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems
  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” if you are treated with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
    • There is a pregnancy exposure registry for women who take DUPIXENT during pregnancy to collect information about the health of you and your baby. Your healthcare provider can enroll you or you may enroll yourself. To get more information about the registry call 1-877-311-8972 or go to https://mothertobaby.org/ongoing-study/dupixent/.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions (hypersensitivity), including a severe reaction known as anaphylaxis. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following symptoms: breathing problems, fever, general ill feeling, swollen lymph nodes, swelling of the face, mouth and tongue, hives, itching, fainting, dizziness, feeling lightheaded (low blood pressure), joint pain, or skin rash.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, and cold sores in your mouth or on your lips.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed. Your healthcare provider will tell you how much DUPIXENT to inject and how often to inject it. DUPIXENT is an injection given under the skin (subcutaneous injection). If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should receive training on the right way to prepare and inject DUPIXENT. Do not try to inject DUPIXENT until you have been shown the right way by your healthcare provider. In children 12 years of age and older, it is recommended that DUPIXENT be administered by or under supervision of an adult. In children younger than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat people aged 6 years and older with moderate-to-severe atopic dermatitis (eczema) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 years of age.

Take This Quiz to Understand Your
Condition

Do you still experience symptoms of constant itching and skin flare-ups while using prescription
topical treatments? Answer a few quick questions to better understand moderate-to-severe eczema
(atopic dermatitis), and use this information to help have a discussion with a doctor.

An Endless Cycle

Does the following cycle sound familiar? In eczema patients, the immune system (coupled with an impaired skin barrier) causes inflammation, contributing to flare-ups on the surface of the skin.

Itching
Immune cells in the deep layers of the skin send inflammatory signals to the surface. This is what makes you think, "I really need to scratch my skin."

Scratching
When you start scratching, you can further break down the outer layer of skin cells and allow germs, irritants, and allergens to penetrate your body.

Inflammatory Signals
The more you scratch, the more your skin breaks down. That brings about more itching. The cycle continues.

Not an actual patient.

Find a Specialist Who
Treats Eczema

Use this Healthgrades™ tool to easily find nearby
specialists with experience in treating children, teens,
and adults with uncontrolled moderate-to-severe
eczema (atopic dermatitis).

Are you sure you want to leave?
Please note: By clicking on this link, you will be leaving this Sanofi-hosted US website and going to another, entirely independent website. Sanofi US and Regeneron provide these links as a service to its website visitors and users; however, they take no responsibility for the information on any website but their own.
Have an Effective Conversation With Your Doctor

Our goal is for you or your loved one to get the most out of your visit to the doctor. Fill out our personalized discussion guide to help yourself have a productive conversation during your next visit.


PERSONALIZE YOUR GUIDE

Get Telemedicine Tips and Techniques